Results 81 to 90 of about 124,788 (331)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Deep Learning for Genomics: From Early Neural Nets to Modern Large Language Models. [PDF]

open access: yesInt J Mol Sci, 2023
Yue T   +7 more
europepmc   +1 more source

Approximation paper, part 1 [PDF]

open access: yes
In this paper we discuss approximations between neural nets, fuzzy expert systems, fuzzy controllers, and continuous ...
Buckley, J. J.
core   +1 more source

Deep neural nets with fixed bias configuration

open access: diamond, 2022
Harbir Antil   +4 more
openalex   +2 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Effects of Biological Adhesion on the Hydrodynamic Characteristics of Different Panel Net Materials: A BP Neural Network Approach

open access: yesJournal of Marine Science and Engineering
Biofouling is a serious problem in marine aquaculture facilities, exerting several negative effects on cage structures. In this study, different materials of nets were placed in the Fujian Sea area of China, and the main biological adhesion species were ...
Yongli Liu   +6 more
doaj   +1 more source

Neural nets on the MPP [PDF]

open access: yes
The Massively Parallel Processor (MPP) is an ideal machine for computer experiments with simulated neural nets as well as more general cellular automata. Experiments using the MPP with a formal model neural network are described.
Hastings, Harold M., Waner, Stefan
core   +1 more source

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