Results 81 to 90 of about 123,000 (283)
Translating Feedforward Neural Nets to SOM-like Maps [PDF]
, 2003 A major disadvantage of feedforward neural networks is still the difficulty to gain insight into their internal functionality. This is much less the case for, e.g., nets that are trained unsupervised, such as Kohonen¿s self-organizing feature maps (SOMs).
Slump, Kees +2 more
core +2 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Journal of Neuroinflammation, 2019 Background and purpose Regulation of neural inflammation is considered as a vital therapeutic target in ischemic stroke. All-trans retinoic acid (atRA), a potent immune modulator, has raised interest in the field of stroke therapy.
Wei Cai +6 more
doaj +1 more source
Approximation paper, part 1 [PDF]
In this paper we discuss approximations between neural nets, fuzzy expert systems, fuzzy controllers, and continuous ...
Buckley, J. J.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A neural network architecture for implementation of expert systems for real time monitoring [PDF]
Since neural networks have the advantages of massive parallelism and simple architecture, they are good tools for implementing real time expert systems.
Ramamoorthy, P. A.
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Quantum deep learning by sampling neural nets with a quantum annealer. [PDF]
Sci Rep, 2023 Higham CF, Bedford A.
europepmc +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Deep Learning for Genomics: From Early Neural Nets to Modern Large Language Models. [PDF]
Int J Mol Sci, 2023 Yue T +7 more
europepmc +1 more source