Results 81 to 90 of about 1,504,339 (298)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Parallel Implementation of Neural Associative Memories on RISC Processors [PDF]
, 1994 Rückert U, Rüping S, Naroska E. Parallel Implementation of Neural Associative Memories on RISC Processors. In: Delgado-Frias JG, Moore WR, eds. VLSI for Neural Networks and Artificial Intelligence.
Delgado-Frias, J.G. +4 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Training artificial neural networks for the implementation of the Petri nets synthesis process
Sistemnì Doslìdženâ ta Informacìjnì TehnologìïThe important task has been solved in this scientific research related to specific development and verification of the fundamental suitability of the method for automatic synthesis of Petri nets based on the functioning of an artificial neural network ...
Alexander Gurskiy +2 more
doaj +1 more source
Quantum deep learning by sampling neural nets with a quantum annealer. [PDF]
Sci Rep, 2023 Higham CF, Bedford A.
europepmc +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Journal of Neuroinflammation, 2019 Background and purpose Regulation of neural inflammation is considered as a vital therapeutic target in ischemic stroke. All-trans retinoic acid (atRA), a potent immune modulator, has raised interest in the field of stroke therapy.
Wei Cai +6 more
doaj +1 more source
Deep Learning for Genomics: From Early Neural Nets to Modern Large Language Models. [PDF]
Int J Mol Sci, 2023 Yue T +7 more
europepmc +1 more source
, 2021 We explore the space of (0, m, 2)-nets in base 2 commonly used for sampling. We present a novel constructive algorithm that can exhaustively generate all nets - - up to m-bit resolution - - and thereby compute the exact number of distinct nets.
Ahmed, Abdalla G.M., Wonka, Peter
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source