Results 111 to 120 of about 5,830,276 (292)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Job-shop scheduling with an adaptive neural network and local search hybrid approach [PDF]
, 2006 This article is posted here with permission from IEEE - Copyright @ 2006 IEEEJob-shop scheduling is one of the most difficult production scheduling problems in industry.
Yang, S +3 more
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata
Neurobiology of DiseaseThe auditory oddball is a mainstay in research on attention, novelty, and sensory prediction. How this task engages subcortical structures like the subthalamic nucleus and substantia nigra pars reticulata is unclear.
Dallas Leavitt +8 more
doaj +1 more source
Frontiers in Computational Neuroscience, 2018 Humans have flexible control over cognitive functions depending on the context. Several studies suggest that the prefrontal cortex (PFC) controls this cognitive flexibility, but the detailed underlying mechanisms remain unclear.
Satoshi Kuroki +2 more
doaj +1 more source
Neural Networks, 2019 It has been known for discrete-time recurrent neural networks (NNs) that binary-state models using the Heaviside activation function (with Boolean outputs 0 or 1) are equivalent to finite automata (level 3 in the Chomsky hierarchy), while analog-state NNs with rational weights, employing the saturated-linear function (with real-number outputs in the ...
openaire +3 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Non-Direct Encoding Method Based on Cellular Automata to Design Neural Network Architectures [PDF]
, 2005 Architecture design is a fundamental step in the successful application of Feed forward Neural Networks. In most cases a large number of neural networks architectures suitable to solve a problem exist and the architecture design is, unfortunately, still ...
Gutiérrez Sánchez, Germán +4 more
core +1 more source
Computer Communication Network Fault Detection Based on Improved Neural Network Algorithm
Electrica, 2022 Dong Sun +3 more
doaj +1 more source