Results 101 to 110 of about 2,150,519 (283)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Auditory oddball responses in the human subthalamic nucleus and substantia nigra pars reticulata
Neurobiology of DiseaseThe auditory oddball is a mainstay in research on attention, novelty, and sensory prediction. How this task engages subcortical structures like the subthalamic nucleus and substantia nigra pars reticulata is unclear.
Dallas Leavitt +8 more
doaj +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
Computer Communication Network Fault Detection Based on Improved Neural Network Algorithm
Electrica, 2022 Dong Sun +3 more
doaj +1 more source
An Improved Recurrent Neural Network for Industrial IoT Botnet Attack Detection
Журнал інженерних наукThis research aims to improve the Industrial Internet of Things (IIoT) security, which fosters technological confidence and promotes expansion. The IIoT is mainly used in manufacturing, oil, and gas to avoid botnet attacks.
G. Suneetha, D.H. Priya
doaj +1 more source
Frontiers in Computational Neuroscience, 2018 Humans have flexible control over cognitive functions depending on the context. Several studies suggest that the prefrontal cortex (PFC) controls this cognitive flexibility, but the detailed underlying mechanisms remain unclear.
Satoshi Kuroki +2 more
doaj +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source
Mean Field Analysis of Neural Networks: A Law of Large Numbers
, 2019 Machine learning, and in particular neural network models, have revolutionized fields such as image, text, and speech recognition. Today, many important real-world applications in these areas are driven by neural networks.
Sirignano, Justin +1 more
core
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source