Results 81 to 90 of about 5,830,276 (292)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Constraint satisfaction adaptive neural network and heuristics combined approaches for generalized job-shop scheduling [PDF]
, 2000 Copyright @ 2000 IEEEThis paper presents a constraint satisfaction adaptive neural network, together with several heuristics, to solve the generalized job-shop scheduling problem, one of NP-complete constraint satisfaction problems.
Yang, S +3 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Neural Processing LettersAbstractWe propose a simple scheme for merging two neural networks trained with different starting initialization into a single one with the same size as the original ones. We do this by carefully selecting channels from each input network. Our procedure might be used as a finalization step after one tries multiple starting seeds to avoid an unlucky ...
Martin Pasen, Vladimír Boza
openaire +3 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Neural Processing Letters, 2002 An associative neural network (ASNN) is an ensemble-based method inspired by the function and structure of neural network correlations in brain. The method operates by simulating the short- and long-term memory of neural networks. The long-term memory is represented by ensemble of neural network weights, while the short-term memory is stored as a pool ...
openaire +5 more sources
Journal of Computer and System Sciences, 2001 This paper initiates the study of quantum computing within the constraints of using a polylogarithmic ($O(\log^k n), k\geq 1$) number of qubits and a polylogarithmic number of computation steps. The current research in the literature has focussed on using a polynomial number of qubits. A new mathematical model of computation called \emph{Quantum Neural
Sanjay Gupta, R. K. P. Zia
openaire +4 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation
npj Parkinson's DiseaseNeuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions.
Atefeh Asadi +5 more
doaj +1 more source