Results 81 to 90 of about 2,445,824 (337)

Static internal representation of dynamic situations reveals time compaction in human cognition

open access: yesJournal of Advanced Research, 2021
Introduction: The human brain has evolved under the constraint of survival in complex dynamic situations. It makes fast and reliable decisions based on internal representations of the environment.
José Antonio Villacorta-Atienza   +9 more
doaj  

Postsynaptic density protein 95 (PSD-95) is transported by KIF5 to dendritic regions

open access: yesMolecular Brain, 2019
Postsynaptic density protein 95 (PSD-95) is a pivotal postsynaptic scaffolding protein in excitatory neurons. Although the transport and regulation of PSD-95 in synaptic regions is well understood, dendritic transport of PSD-95 before synaptic ...
Ki-Seo Yoo   +6 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Electrophysiological approaches to informing therapeutic interventions with deep brain stimulation

open access: yesnpj Parkinson's Disease
Neuromodulation therapy comprises a range of non-destructive and adjustable methods for modulating neural activity using electrical stimulations, chemical agents, or mechanical interventions.
Atefeh Asadi   +5 more
doaj   +1 more source

Neural Network Based System Identification of an Axis of Car Suspension System [PDF]

open access: yes, 2008
Neural networks system identification have been widely used for estimate the nonlinear model of system. In this paper, multilayer perceptron neural network is used for identifying the Nonlinear AutoRegressive with eXogenous input (NARX) model of a ...
bin Rahmat, Mohd. Fua’ad   +1 more
core  

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response

open access: yesNature Communications, 2018
Brain circuits that control innate fear response are essential for an animal’s survival. Here, the authors report how the anterior cingulate cortex and its projection to amygdala control the innate fear response in mice.
Jinho Jhang   +5 more
doaj   +1 more source

Generating Neural Networks with Neural Networks

open access: yes, 2018
Hypernetworks are neural networks that generate weights for another neural network. We formulate the hypernetwork training objective as a compromise between accuracy and diversity, where the diversity takes into account trivial symmetry transformations of the target network. We explain how this simple formulation generalizes variational inference.
openaire   +2 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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