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Long-term motor training can cause functional and structural changes in the human brain. Assessing how the training of specific movements affects specific parts of the neural circuitry is essential to understand better the underlying mechanisms of motor ...
Tomoyo Morita+2 more
doaj +1 more source
Mathematical Neural Networks [PDF]
ANNs succeed in several tasks for real scenarios due to their high learning abilities. This paper focuses on theoretical aspects of ANNs to enhance the capacity of implementing those modifications that make ANNs absorb the defining features of each scenario.
openaire +3 more sources
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Model-free decision-making underlies motor errors in rapid sequential movements under threat
Our movements, especially sequential ones, are usually goal-directed, i.e., coupled with task-level goals. Consequently, cognitive strategies for decision-making and motor performance are likely to influence each other. However, evidence linking decision-
Pranav Sankhe, Masahiko Haruno
doaj +1 more source
Approximate Bisimulation Relations for Neural Networks and Application to Assured Neural Network Compression [PDF]
In this paper, we propose a concept of approximate bisimulation relation for feedforward neural networks. In the framework of approximate bisimulation relation, a novel neural network merging method is developed to compute the approximate bisimulation error between two neural networks based on reachability analysis of neural networks.
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Over the past three decades numerous imaging studies have revealed structural and functional brain abnormalities in patients with neuropsychiatric diseases. These structural and functional brain changes are frequently found in multiple, discrete brain areas and may include frontal, temporal, parietal and occipital cortices as well as subcortical brain ...
Edward T. Bullmore+1 more
openaire +3 more sources
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau+11 more
wiley +1 more source
The aim of this study was to identify the functional connectivity and networks utilized during tool-use in real assembly workers. These brain networks have not been elucidated because the use of tools in real-life settings is more complex than that in ...
Seira Taniguchi+4 more
doaj +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source