Faf2 is required for neural differentiation in embryonic neural progenitor cells [PDF]
Frontiers in Cell and Developmental BiologyNeural progenitor cell differentiation is a complex process requiring the proper integration of instructive and permissive factors. Instructive cues including signaling molecules and transcription factor networks have been well studied in this context ...
Anneke Dixie Kakebeen +3 more
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Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation [PDF]
Scientific ReportsThe differentiation of neural progenitor cells into glial and neuronal lineages is a fundamental process in neurodevelopment. This complex process is tightly regulated by several signaling pathways, including calcium signaling. Calcium signaling not only
Silke B. Chalmers +4 more
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Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells
Brazilian Journal of Otorhinolaryngology, 2022 Introduction: Inner ear progenitor cells have the potential for multi-directional differentiation. Retinoic acid is an important requirement for the development of the inner ear.
Minyun Chen, Jianmin Huang
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Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a. [PDF]
PLoS ONE, 2017 In the developing neocortex, cells in the ventricular/subventricular zone are largely multipotent neural stem cells and neural progenitor cells. These cells undergo self-renewal at the early stage of embryonic development to amplify the progenitor pool ...
Dong Sun +6 more
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MicroRNA profiling in subventricular zone after stroke: MiR-124a regulates proliferation of neural progenitor cells through Notch signaling pathway. [PDF]
PLoS ONE, 2011 The Notch signaling pathway regulates adult neurogenesis under physiological and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules that regulate gene expression. The present study investigated the effect of miR-124a on the Notch
Xian Shuang Liu +9 more
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Soluble Nogo receptor 1 fusion protein protects neural progenitor cells in rats with ischemic stroke
Neural Regeneration Research, 2019 Soluble Nogo66 receptor-Fc protein (sNgR-Fc) enhances axonal regeneration following central nervous system injury. However, the underlying mechanisms remain unclear.
Hai-Wei He +6 more
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Neuregulin 1 Type II-ErbB Signaling Promotes Cell Divisions Generating Neurons from Neural Progenitor Cells in the Developing Zebrafish Brain. [PDF]
PLoS ONE, 2015 Post-mitotic neurons are generated from neural progenitor cells (NPCs) at the expense of their proliferation. Molecular and cellular mechanisms that regulate neuron production temporally and spatially should impact on the size and shape of the brain ...
Tomomi Sato +6 more
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Pannexin 1 regulates postnatal neural stem and progenitor cell proliferation
Neural Development, 2012 Background Pannexin 1 forms ion and metabolite permeable hexameric channels and is abundantly expressed in the brain. After discovering pannexin 1 expression in postnatal neural stem and progenitor cells we sought to elucidate its functional role in ...
Wicki-Stordeur Leigh E +4 more
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Frontiers in Cell and Developmental Biology, 2020 Human pluripotent stem cells can be differentiated into midbrain dopaminergic (mDA) neurons by directing cells through a floor plate progenitor stage. The developmental identity of mDA neurons produced using floor plate protocols is similar to substantia
Nicola J. Drummond +6 more
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Genome-wide gene amplification during differentiation of neural progenitor cells in vitro. [PDF]
PLoS ONE, 2012 DNA sequence amplification is a phenomenon that occurs predictably at defined stages during normal development in some organisms. Developmental gene amplification was first described in amphibians during gametogenesis and has not yet been described in ...
Ulrike Fischer +5 more
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