The species specific effects of Mesenchymal stem cell conditioned medium on proliferating mouse and rat adult neural stem, progenitor cells [PDF]
Adult stem cells reside in different tissues and organs of the adult organism. Among these cells are Mesenchymal stem cells (MSCs) and neural stem and progenitor cells (NSPCs).
Dechant, Franz - Xaver
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Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J +24 more
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The accurate generation of an appropriate number of different neuronal and glial subtypes is fundamental to normal brain functions and requires tightly orchestrated spatial and temporal developmental programmes to maintain the balance between the ...
Pengcheng Shu +13 more
doaj +1 more source
L1 retrotransposition in human neural progenitor cells [PDF]
Long interspersed element 1 (LINE-1 or L1) retrotransposons have markedly affected the human genome. L1s must retrotranspose in the germ line or during early development to ensure their evolutionary success, yet the extent to which this process affects somatic cells is poorly understood.
Nicole G, Coufal +9 more
openaire +2 more sources
Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M. +18 more
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Potential of Neural Stem Cells for the Treatment of Brain Tumors
Neural stem cells (NSCs) are self-renewing multipotent cells that generate the main phenotypes of the nervous system, neurons, astrocytes and oligodendrocytes.
P. Taupin
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A Sox2 BAC transgenic approach for targeting adult neural stem cells. [PDF]
The transcription factor gene Sox2 is expressed in embryonic neural stem/progenitor cells and previous evidence suggests that it is also expressed in adult neural stem cells. To target Sox2-expressing neural stem/progenitor cells in a temporal manner, we
Wenfei Kang, Jean M Hébert
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Comparative Analysis of the Frequency and Distribution of Stem and Progenitor Cells in the Adult Mouse Brain [PDF]
cells (NSCs) and progenitor cells, but it cannot discriminate between these two populations. Given two assays have purported to overcome this shortfall, we performed a comparative analysis of the distribution and frequency of NSCs and progenitor ...
Golmohammadi, Mohammed G. +17 more
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A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells [PDF]
Neurogenesis is initiated by a set of basic Helix-Loop-Helix (bHLH) transcription factors that specify neural progenitors and allow them to generate neurons in multiple rounds of asymmetric cell division.
Heinrich Reichert +25 more
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Isolation of neural stem and oligodendrocyte progenitor cells from the brain of live rats [PDF]
Summary Postnatal brain neural stem and progenitor cells (NSPCs) cluster in anatomically inaccessible stem cell niches, such as the subependymal zone (SEZ). Here, we describe a method for the isolation of NSPCs from live animals, which we term “milking.”
Paraskevi Kakouri +13 more
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