Results 41 to 50 of about 6,298,151 (304)

ID3-depleted human induced pluripotent stem cell–derived neural stem/progenitor cells promote neurorepair

Neural Regeneration Research
Human induced pluripotent stem cell–derived neural stem/progenitor cells are used in cell-replacement and regenerative therapeutic strategies after traumatic central nervous system injury.
Jia-Di Lin, Ruba Hammad, Prateek Kumar, Pedro Manzitti, Kexin Wu, Jamal Alzubi, Andreas Vlachos, Toni Cathomen, Armin Blesch, Yu-Hsuan Chu, Christian Schachtrup   +10 more
doaj   +1 more source

Transplantation of Human Neural Progenitor Cells to the Vitreous Cavity of the Royal College of Surgeons Rat

Cell Transplantation, 2001
Human neural progenitor cells, originally isolated from prenatal donor tissue at 17 weeks of development, were cultured as neurospheres and transplanted to the vitreous cavity of dystrophic Royal College of Surgeons rats with, or without, cyclosporin A ...
Hiroyuki Mizumoto, Keiko Mizumoto, Simon J. O. Whiteley, Marie Shatos, Henry Klassen, Michael J. Young   +5 more
doaj   +1 more source

A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in Drosophila [PDF]

, 2013
The neurons and glial cells of the Drosophila brain are generated by neural stem cell-like progenitors during two developmental phases, one short embryonic phase and one more prolonged postembryonic phase.
Reichert, Heinrich, Viktorin, Gudrun, Riebli, Nadia, Riebli N, Reichert H, Viktorin G   +5 more
core   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

Critical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD, Khari Johnson, MS, Ryan M. Schweller, PhD, Rachel Chapla, MS, Brian E. Mace, BS, Daniel T. Laskowitz, MD, Jennifer L. West, PhD   +6 more
doaj   +1 more source

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Stem Cells, Neural Progenitors, and Engineered Stem Cells [PDF]

, 2014
Human pluripotent stem cells (hPSCs ) have the unique potential to form every cell type in the body. This potential provides opportunities for generating human progenitors and other differentiated cell types for understanding human development and for use in cell type-specific therapies. Equally important is the ability to engineer stem cells and their
Raj R, Rao, Shilpa, Iyer
openaire   +2 more sources

A chemical approach to “rewire” neural progenitor cells [PDF]

Cell Research, 2014
Generation of neural progenitor cells (NPCs) from pluripotent stem cells including ESCs and iPSCs and derivation of NPCs from somatic tissues have been considered promising approaches that could be used therapeutically to restore function in patients suffering neurodegenerative diseases. A new study published in Cell Research shows, for the first time,
Min-Zu, Wu, Mo, Li, Guang-Hui, Liu, Juan Carlos, Izpisua Belmonte   +3 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Stable and efficient generation of functional iPSC-derived neural progenitor cell rosettes through regulation of collective cell-cell behavior

Frontiers in Bioengineering and Biotechnology
Although the potential of stem cells to differentiate into several cell types has shown promise in regenerative medicine, low differentiation efficiency and poor reproducibility significantly limit their practical application.
Mee-Hae Kim, Naruchit Thanuthanakhun, Masahiro Kino-oka, Masahiro Kino-oka   +3 more
doaj   +1 more source