Results 71 to 80 of about 6,298,151 (304)

Neural stem and progenitor cells in health and disease

WIREs Systems Biology and Medicine, 2013
Neural stem/progenitor cells (NSPCs) have the potential to differentiate into neurons, astrocytes, and/or oligodendrocytes. Because these cells can be expanded in culture, they represent a vast source of neural cells. With the recent discovery that patient fibroblasts can be reprogrammed directly into induced NSPCs, the regulation of NSPC fate and ...
Ian, Ladran, Ngoc, Tran, Aaron, Topol, Kristen J, Brennand   +3 more
openaire   +2 more sources

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Mathematical modeling supports substantial mouse neural progenitor cell death

Neural Development, 2009
Background Existing quantitative models of mouse cerebral cortical development are not fully constrained by experimental data. Results Here, we use simple difference equations to model neural progenitor cell fate decisions, incorporating intermediate ...
MacMillan Hugh R, McConnell Michael J, Chun Jerold   +2 more
doaj   +1 more source

Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]

, 2011
Background: Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis.
Kelly, RDW, Stuart Egginton, Rae, Peter, Richard DW Kelly, StJohn, JC, Peter C Rae, St. John, Justin C., Justin C St John, Rae, Peter C., Egginton, Stuart, Rae, PC, Egginton, S, Kelly, Richard D. W., St John, JC   +13 more
core   +1 more source

Organoids as Building Blocks for Adaptive and Resilient Biohybrid Robots

Advanced Materials Technologies, EarlyView.
ABSTRACT Biohybrid robots combine engineered living tissues with synthetic materials and have emerged as a promising class of soft robotic systems capable of mimicking biological functions such as biodegradability, energy efficiency and flexible motions. By integrating biological and synthetic components, these systems leverage complementary properties
Antonia Georgopoulou
wiley   +1 more source

Bone marrow derived cells as endothelial precursors and the role of multi-potent progenitor cells in repairing ischaemic tissues. [PDF]

, 2007
PhDIntroduction: Atherosclerosis and its complications are a major cause of death and disability and it remains a major challenge to develop new therapies for patients with irreversible end organ damage and ongoing ischaemia.
Wragg, Andrew
core   +2 more sources

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation

Scientific Reports
The differentiation of neural progenitor cells into glial and neuronal lineages is a fundamental process in neurodevelopment. This complex process is tightly regulated by several signaling pathways, including calcium signaling. Calcium signaling not only
Silke B. Chalmers, Mélanie Robitaille, Francisco Sadras, Sarah J. Roberts-Thomson, Gregory R. Monteith   +4 more
doaj   +1 more source

Computational prediction of neural progenitor cell fates [PDF]

Nature Methods, 2010
Understanding how stem and progenitor cells choose between alternative cell fates is a major challenge in developmental biology. Efforts to tackle this problem have been hampered by the scarcity of markers that can be used to predict cell division outcomes.
Cohen, Andrew R., Gomes, F.L.A.F., Roysam, B., Cayouette, M.   +3 more
openaire   +2 more sources

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source