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2012
Regeneration of the nervous system requires either the repair or replacement of nerve cells that have been damaged by injury or disease. While lower organisms possess extensive capacity for neural regeneration, evolutionarily higher organisms including humans are limited in their ability to regenerate nerve cells, posing significant issues for the ...
Melissa M, Steward +2 more
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Regeneration of the nervous system requires either the repair or replacement of nerve cells that have been damaged by injury or disease. While lower organisms possess extensive capacity for neural regeneration, evolutionarily higher organisms including humans are limited in their ability to regenerate nerve cells, posing significant issues for the ...
Melissa M, Steward +2 more
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Approaches for Neural Tissue Regeneration
Stem Cell Reviews and Reports, 2013There is currently no treatment for neurodegenerative diseases such as Parkinson's or Alzheimer's diseases. While spinal cord injury has no treatment either, nerve injuries are being treated with autologous grafts, a procedure that in turn translates into a loss of function in the donor area.
Loïc, Binan +3 more
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Neural regeneration in gastropod molluscs
Progress in Neurobiology, 1995Snails recover function following a variety of neural injuries. They grow new tentacles with associated tentacle ganglia, selectively reinnervate peripheral targets, repair central connections and may even replace lost neurons and ganglia. The plasticity revealed in their responses to neural injury is an extreme expression of the adaptability observed ...
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How the Neural Retina Regenerates
2000The rules that govern cellular behavior during development and regeneration of tissues are complex and enigmatic, but substantial progress is being made toward understanding the molecular basis of proliferation and differentiation. Although most of the recent mechanistic insights have been gained from studies of embryonic development, the capacity of ...
P A, Raymond, P F, Hitchcock
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A regenerating spiking neural network
Neural Networks, 2005Due to their distributed architecture, artificial neural networks often show a graceful performance degradation to the loss of few units or connections. Living systems also display an additional source of fault-tolerance obtained through distributed processes of self-healing: defective components are actively regenerated.
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Neural Modulation of Regenerating Adrenal Transplants
Endocrine Research, 2000In addition to control of adrenal cortical steroidogenesis by adrenocorticotropic hormone (ACTH) and angiotensin 11, the intact rat adrenal gland is extensively innervated by a variety of nerve fibers that have been implicated in modulating adrenal cortical function (reviewed in 1).
Y M, Ulrich-Lai, W C, Engeland
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Functional Neural Regeneration after Pulmonary Denervation
Chest, 1970Reimplantation of the lung produces complete interruption of all ipsilateral pulmonary nerves. A consequence of this denervation is the loss of the pulmonary stretch-receptor (Hering-Breuer) reflex. Forty-four dogs were studied for stretch-receptor activity one day to 17 months after unilateral orthotopic pulmonary reimplantation.
G E, Duvoisin +3 more
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The Molecular Basis of Neural Regeneration
Neurosurgery, 2003THE CENTRAL NERVOUS SYSTEM (CNS) is incapable of meaningful regeneration of lost neurons or axonal and dendritic connections after injury. This often results in permanent and severe loss of neurological function. The CNS regenerative process is unsuccessful for at least three reasons: neurons are highly susceptible to death after CNS injury; the CNS ...
W Bradley, Jacobs, Michael G, Fehlings
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Neural ECM in regeneration and rehabilitation
2014Neural extracellular matrix (ECM) is different from the normal ECM in other organs in that it has low fibrous protein content and high carbohydrate content. One of the key carbohydrate components in the brain ECM is chondroitin sulfate proteoglycans (CSPGs).
Sujeong Yang +2 more
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Advances in neural regeneration.
Annals of the Royal Australasian College of Dental Surgeons, 1991The familiar concept of the inability of injured neurones in the mammalian central nervous system to regenerate has been deep-rooted in the minds of neurologists since the time of Ramon y Cajal. However, modern research techniques and novel experimental manipulations have begun to reveal the existence of a robust potential for axonal regrowth even in ...
So, KF, Cho, EY
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