Results 11 to 20 of about 2,833,598 (231)

Respiratory drive: a journey from health to disease

open access: yesJournal of Intensive Care
Respiratory drive is defined as the intensity of respiratory centers output during the breath and is primarily affected by cortical and chemical feedback mechanisms.
Dimitrios Georgopoulos   +3 more
doaj   +2 more sources

Clinical risk factors for increased respiratory drive in intubated hypoxemic patients

open access: yesCritical Care, 2023
Background There is very limited evidence identifying factors that increase respiratory drive in hypoxemic intubated patients. Most physiological determinants of respiratory drive cannot be directly assessed at the bedside (e.g., neural inputs from chemo-
Elena Spinelli   +13 more
doaj   +1 more source

Ventilatory neural drive in chronically hypercapnic patients with COPD: effects of sleep and nocturnal noninvasive ventilation

open access: yesEuropean Respiratory Review, 2022
Sleep brings major challenges for the control of ventilation in humans, particularly the regulation of arterial carbon dioxide pressure (PaCO2). In patients with COPD, chronic hypercapnia is associated with increased mortality.
Alexandra McCartney   +7 more
doaj   +1 more source

Effect of diaphragm fatigue on neural respiratory drive

open access: yes, 2001
To test the hypothesis that diaphragm fatigue leads to an increase in neural respiratory drive, we measured the esophageal diaphragm electromyogram (EMG) during CO2 rebreathing before and after diaphragm fatigue in six normal subjects.
N. Hart   +11 more
core   +6 more sources

Oxygen therapy in respiratory disorders [PDF]

open access: yes, 2012
PhDOxygen therapy remains a cornerstone of medical practice and is generally regarded as being safe. However, there is a lack of clinical evidence to support the routine use of oxygen therapy, and in certain conditions, injudicious oxygen may cause harm.
Wijesinghe, Meme
core   +4 more sources

Neural Respiratory Drive and Arousal in Patients with Obstructive Sleep Apnea Hypopnea. [PDF]

open access: yesSleep, 2015
Study Objectives: It has been hypothesized that arousals after apnea and hypopnea events in patients with obstructive sleep apnea are triggered when neural respiratory drive exceeds a certain level, but this hypothesis is based on esophageal pressure ...
Xiao SC   +5 more
europepmc   +2 more sources

Neural activity induced by sensory stimulation can drive large-scale cerebrospinal fluid flow during wakefulness in humans.

open access: yesPLoS Biology, 2023
Cerebrospinal fluid (CSF) flow maintains healthy brain homeostasis, facilitating solute transport and the exchange of brain waste products. CSF flow is thus important for brain health, but the mechanisms that control its large-scale movement through the ...
Stephanie D Williams   +6 more
doaj   +2 more sources

Respiratory drive in the acute respiratory distress syndrome: pathophysiology, monitoring, and therapeutic interventions [PDF]

open access: yes, 2020
Neural respiratory drive, i.e., the activity of respiratory centres controlling breathing, is an overlooked physiologic variable which affects the pathophysiology and the clinical outcome of acute respiratory distress syndrome (ARDS).
Brodie D.   +4 more
core   +1 more source

Chronic pulmonary fibrosis alters the functioning of the respiratory neural network

open access: yesFrontiers in Physiology, 2023
Some patients with idiopathic pulmonary fibrosis present impaired ventilatory variables characterised by low forced vital capacity values associated with an increase in respiratory rate and a decrease in tidal volume which could be related to the ...
Céline-Hivda Yegen   +8 more
doaj   +1 more source

Neural Respiratory Drive in Patients with COPD during Exercise Tests

open access: yes, 2011
Background: It is unknown whether neural drive is comparable in constant rate and incremental exercise tests. Few data have previously been available to address this question because of the lack of reliable methods to assess neural respiratory drive in ...
Jolley, C; id_orcid   +6 more
core   +2 more sources

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