Results 21 to 30 of about 2,833,598 (231)

Physiological mechanisms of dyspnea during exercise with external thoracic restriction: role of increased neural respiratory drive.

J Appl Physiol (1985), 2014
Mendonca CT, Schaeffer MR, Riley P, Jensen D.   +3 more
europepmc   +2 more sources

A bilateral cortico-bulbar network associated with breath holding in humans, determined by functional magnetic resonance imaging [PDF]

, 2008
Few tasks are simpler to perform than a breath hold; however, the neural basis underlying this voluntary inhibitory behaviour, which must suppress spontaneous respiratory motor output, is unknown.
Frackowiak, Richard S J, Frackowiak, Richard S.J., Corfield, Douglas R., Corfield, Douglas, Adams, Lewis, Frackowiak, Richard S. J., McKay, Leanne C.   +6 more
core   +1 more source

Dyspnea and Exercise Limitation in Mild COPD: The Value of CPET

Frontiers in Medicine, 2020
The majority of smokers with chronic obstructive pulmonary disease (COPD) have mild airflow limitation as determined by simple spirometry. Although small airway dysfunction is the hallmark of COPD, many studies attest to complex heterogeneous ...
Matthew D. James, Kathryn M. Milne, Kathryn M. Milne, Devin B. Phillips, J. Alberto Neder, Denis E. O'Donnell   +5 more
doaj   +1 more source

Neural mechanisms underlying breathing complexity. [PDF]

PLoS ONE, 2013
Breathing is maintained and controlled by a network of automatic neurons in the brainstem that generate respiratory rhythm and receive regulatory inputs.
Agathe Hess, Lianchun Yu, Isabelle Klein, Marine De Mazancourt, Gilles Jebrak, Hervé Mal, Olivier Brugière, Michel Fournier, Maurice Courbage, Gaelle Dauriat, Elisabeth Schouman-Clayes, Christine Clerici, Laurence Mangin   +12 more
doaj   +1 more source

Systems for the management of respiratory disease in primary care - an international series: United Kingdom [PDF]

, 2010
INTRODUCTION: The UK National Health Service (NHS) is essentially publicly funded through general taxation. Challenges facing the NHS include the rise in prevalence of long-term conditions and financial pressures.
Allison Worth, Mark Levy, Worth, Allison, Levy, Mark L., Fletcher, Monica, Pinnock, Hilary, Aziz Sheikh, Monica Fletcher, Hilary Pinnock, Pinnock, Hilary; id_orcid, Hoskins, Gaylor, Levy, Mark, Gaylor Hoskins, Sheikh, Aziz, Levy, Mark L   +14 more
core   +1 more source

Potential Role of the Retrotrapezoid Nucleus in Mediating Cardio-Respiratory Dysfunction in Heart Failure With Preserved Ejection Fraction

Frontiers in Physiology, 2022
A strong association between chemoreflex hypersensitivity, disordered breathing, and elevated sympathetic activity has been shown in experimental and human heart failure (HF).
Camilo Toledo, Camilo Toledo, Domiziana Ortolani, Fernando C. Ortiz, Noah J. Marcus, Rodrigo Del Rio, Rodrigo Del Rio, Rodrigo Del Rio   +7 more
doaj   +1 more source

Respiratory effects of kynurenic acid microinjected into the ventromedullary surface of the rat

Brazilian Journal of Medical and Biological Research, 1998
Several studies demonstrate that, within the ventral medullary surface (VMS), excitatory amino acids are necessary components of the neural circuits involved in the tonic and reflex control of respiration and circulation.
F.P. Tolentino-Silva, A.K. Russo, S.L. Cravo, O.U. Lopes   +3 more
doaj   +1 more source

The Consequences of Preterm Birth and Chorioamnionitis on Brainstem Respiratory Centers: Implications for Neurochemical Development and Altered Functions by Inflammation and Prostaglandins

Frontiers in Cellular Neuroscience, 2018
Preterm birth is a major cause for neonatal morbidity and mortality, and is frequently associated with adverse neurological outcomes. The transition from intrauterine to extrauterine life at birth is particularly challenging for preterm infants. The main
Vanesa Stojanovska, Suzanne L. Miller, Suzanne L. Miller, Stuart B. Hooper, Stuart B. Hooper, Graeme R. Polglase, Graeme R. Polglase   +6 more
doaj   +1 more source

Neural respiratory drive in obesity

, 2009
BACKGROUND: The load imposed on ventilation by increased body mass contributes to the respiratory symptoms caused by obesity. A study was conducted to quantify ventilatory load and respiratory drive in obesity in both the upright and supine postures ...
Seymour, J, Polkey, M I, Moxham, J, Roughton, M, Steier, J; id_orcid, Jolley, C J; id_orcid   +5 more
core   +1 more source

Myths and methodologies: Invasive and non‐invasive assessment of respiratory muscle activity in humans

Experimental Physiology
Survival relies on neural respiratory drive from the medullary respiratory centres to activate the respiratory muscles for breathing. Accurate assessment of respiratory muscle activity, as an estimate of neural respiratory drive in humans, will ...
Anna L. Hudson, Caroline J. Jolley, Simon C. Gandevia, Jane E. Butler   +3 more
doaj   +1 more source