Results 1 to 10 of about 1,045,843 (356)
AbstractNeural stem cells (NSCs) have the ability to self‐renew, and are capable of differentiating into neurones, astrocytes and oligodendrocytes. Such cells have been isolated from the developing brain and more recently from the adult central nervous system. This review aims to provide an overview of the current research in this evolving area.
Tanja Zigova +2 more
+7 more sources
The adult vertebrate central nervous system (CNS) consists of four major differentiated cell types: neurons, astrocytes, oligodendrocytes and ependymal cells. Historically, there has been a disagreement on how these differentiated cell types are generated in the CNS. Progress remains hindered by the complexity of cell structure in this system, the lack
Rossella Galli +3 more
+9 more sources
Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System [PDF]
Clas B. Johansson +5 more
openalex +2 more sources
Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior repair strategies.
Lin Zhong +9 more
semanticscholar +1 more source
Deep learning-based predictive identification of neural stem cell differentiation
The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in devising potential cell-based therapeutic strategies for central nervous system (CNS) diseases, however, the determination and prediction of differentiation is ...
Yanjing Zhu +5 more
semanticscholar +1 more source
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation [PDF]
Anna V. Molofsky +5 more
openalex +2 more sources
Background Immune cells play crucial roles after spinal cord injury (SCI). However, incomplete knowledge of immune contributions to injury and repair hinders development of SCI therapies.
Elizabeth S. Fisher +7 more
doaj +1 more source
Control the Neural Stem Cell Fate with Biohybrid Piezoelectrical Magnetite Micromotors.
Inducing neural stem cells to differentiate and replace degenerated functional neurons represents the most promising approach for neural degenerative diseases including Parkinson's disease, Alzheimer's disease, etc.
Lu Liu +13 more
semanticscholar +1 more source
Electrical Stimulation Promotes Stem Cell Neural Differentiation in Tissue Engineering
Nerve injuries and neurodegenerative disorders remain serious challenges, owing to the poor treatment outcomes of in situ neural stem cell regeneration. The most promising treatment for such injuries and disorders is stem cell-based therapies, but there ...
Hong Cheng +3 more
semanticscholar +1 more source
Background Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are common age-related neurodegenerative diseases comprising Lewy body spectrum disorders associated with cortical and subcortical Lewy body pathology.
Haitao Tu +10 more
doaj +1 more source

