The adult mouse hippocampal progenitor is neurogenic but not a stem cell [PDF]
, 2005 The aim of this investigation was to characterize the proliferative precursor cells in the adult mouse hippocampal region. Given that a very large number of new hippocampal cells are generated over the lifetime of an animal, it is predicted that a neural
Bartlett, P. F., Bull, N. D.
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The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation [PDF]
, 2017 Rapidity and specificity are characteristic features of proteolysis mediated by the ubiquitin-proteasome system. Therefore, the UPS is ideally suited for the remodeling of the embryonic stem cell proteome during the transition from pluripotent to ...
Cuevas, E +6 more
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FGF-2-Responsive Neural Stem Cell Proliferation Requires CCg, a Novel Autocrine/Paracrine Cofactor [PDF]
, 2000 We have purified and characterized a factor, from the conditioned medium of neural stem cell cultures, which is required for fibroblast growth factor 2's (FGF-2) mitogenic activity on neural stem cells. This autocrine/paracrine cofactor is a glycosylated
Altman +62 more
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Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]
, 2010 Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
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High-throughput continuous dielectrophoretic separation of neural stem cells. [PDF]
, 2019 We created an integrated microfluidic cell separation system that incorporates hydrophoresis and dielectrophoresis modules to facilitate high-throughput continuous cell separation. The hydrophoresis module consists of a serpentine channel with ridges and
Adams, Tayloria NG +6 more
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Molecular NeurodegenerationBackground The expansion of GGC repeats (typically exceeding 60 repeats) in the 5’ untranslated region (UTR) of the NOTCH2NLC gene (N2C) is linked to N2C-related repeat expansion disorders (NREDs), such as neuronal intranuclear inclusion disease (NIID ...
Haitao Tu +17 more
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Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. [PDF]
, 2019 The goal of stem cell therapy for spinal cord injury (SCI) is to restore motor function without exacerbating pain. Induced pluripotent stem cells (iPSC) may be administered by autologous transplantation, avoiding immunologic challenges.
Brifault, Coralie +11 more
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Cell Transplantation, 2016 Neuronal progenitor cells (NPCs) derived from human embryonic stem cells (hESCs) are an excellent cell source for transplantation therapy due to their availability and ethical acceptability.
Lifeng Qiu +6 more
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Mitochondrial Stress Response in Neural Stem Cells Exposed to Electronic Cigarettes. [PDF]
, 2019 Stem cells provide a sensitive model to study exposure to toxicants, such as cigarette smoke. Electronic cigarettes (ECs) are popular nicotine delivery devices, often targeted to youth and pregnant mothers. However, little is known about how chemicals in
Chaili, Angela +5 more
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LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons
Protein & Cell, 2020 Fang Yuan +6 more
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