Results 1 to 10 of about 1,438,323 (398)

Neural Stem Cells [PDF]

The Journal of Pathology, 2002
AbstractNeural stem cells (NSCs) have the ability to self‐renew, and are capable of differentiating into neurones, astrocytes and oligodendrocytes. Such cells have been isolated from the developing brain and more recently from the adult central nervous system. This review aims to provide an overview of the current research in this evolving area.
Tanja Zigova, Paul R. Sanberg, Juan Sanchez‐Ramos   +2 more
  +7 more sources

Neural Stem Cells [PDF]

Bone Marrow Transplantation, 2003
The adult vertebrate central nervous system (CNS) consists of four major differentiated cell types: neurons, astrocytes, oligodendrocytes and ependymal cells. Historically, there has been a disagreement on how these differentiated cell types are generated in the CNS. Progress remains hindered by the complexity of cell structure in this system, the lack
Rossella Galli, Angela Gritti, Luca Bonfanti, Angelo L. Vescovi   +3 more
  +9 more sources

Topological defect launches 3D mound in the active nematic sheet of neural progenitors [PDF]

, 2016
Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cultured stem cells at the level of morphology and macroscopic patterns resulting from cell-to-cell interactions remain largely qualitative, even though they are the simplest ...
Kageyama, Ryoichiro, Kawaguchi, Kyogo, Sano, Masaki   +2 more
arxiv   +3 more sources

Single cell profiling of CD45+ spinal cord cells reveals microglial and B cell heterogeneity and crosstalk following spinal cord injury

Journal of Neuroinflammation, 2022
Background Immune cells play crucial roles after spinal cord injury (SCI). However, incomplete knowledge of immune contributions to injury and repair hinders development of SCI therapies.
Elizabeth S. Fisher, Matthew A. Amarante, Natasha Lowry, Steven Lotz, Farhad Farjood, Sally Temple, Caitlin E. Hill, Thomas R. Kiehl   +7 more
doaj   +1 more source

Sorting live stem cells based on Sox2 mRNA expression. [PDF]

, 2012
PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
C Giachino, D Velluto, DH Mathews, Diana Velluto, E Pastrana, FW King, Hans M. Larsson, I Chambers, Jeffrey A. Hubbell, Joseph Najbauer, K Takahashi, LA Boyer, M Zuker, Marta Roccio, Matthias P. Lutolf, N Nitin, O Basak, P Ellis, Peter Frey, S Okumura-Nakanishi, S Tyagi, S Viswanathan, Seung Tae Lee, ST Lee, V Graham, WJ Rhee, WJ Rhee   +26 more
core   +17 more sources

Increased expression of pathological markers in Parkinson’s disease dementia post-mortem brains compared to dementia with Lewy bodies

BMC Neuroscience, 2022
Background Parkinson’s disease (PD) and dementia with Lewy bodies (DLB) are common age-related neurodegenerative diseases comprising Lewy body spectrum disorders associated with cortical and subcortical Lewy body pathology.
Haitao Tu, Zhi Wei Zhang, Lifeng Qiu, Yuning Lin, Mei Jiang, Sook-Yoong Chia, Yanfei Wei, Adeline S. L. Ng, Richard Reynolds, Eng-King Tan, Li Zeng   +10 more
doaj   +1 more source

The Effects of Extrinsic and Intrinsic Factors on Neurogenesis

Cells, 2023
In the mammalian brain, neurogenesis is maintained throughout adulthood primarily in two typical niches, the subgranular zone (SGZ) of the dentate gyrus and the subventricular zone (SVZ) of the lateral ventricles and in other nonclassic neurogenic areas (
Mei Jiang, Se Eun Jang, Li Zeng
doaj   +1 more source

Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells

APL Bioengineering, 2023
During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This organized vasculature
Taylor Bertucci, Shravani Kakarla, Max A. Winkelman, Keith Lane, Katherine Stevens, Steven Lotz, Alexander Grath, Daylon James, Sally Temple, Guohao Dai   +9 more
doaj   +1 more source

NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits

Journal of Neuroinflammation, 2022
Background Alcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon cessation. This process is associated with the activation of NLRP3 inflammasome-mediated responses.
Ziyi Li, Olivia Ewi Vidjro, Gengni Guo, Yanfeng Du, Yao Zhou, Qian Xie, Jiaxin Li, Keqiang Gao, Li Zhou, Tengfei Ma   +9 more
doaj   +1 more source

Flexibility of Neural Stem Cells [PDF]

Frontiers in Physiology, 2011
Embryonic cortical neural stem cells are self-renewing progenitors that can differentiate into neurons and glia. We generated neurospheres from the developing cerebral cortex using a mouse genetic model that allows for lineage selection and found that the self-renewing neural stem cells are restricted to Sox2 expressing cells.
Remboutsika, Eumorphia, Elkouris, Maximilianos, Iulianella, Angelo, Andoniadou, Cynthia L, Poulou, Maria, Mitsiadis, Thimios A, Trainor, Paul A, Lovell-Badge, Robin   +7 more
openaire   +5 more sources