Results 121 to 130 of about 1,438,323 (398)
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
miR-381 Regulates Neural Stem Cell Proliferation and Differentiation via Regulating Hes1 Expression
PLoS ONE, 2015 Neural stem cells are self-renewing, multipotent and undifferentiated precursors that retain the capacity for differentiation into both glial (astrocytes and oligodendrocytes) and neuronal lineages.
Xiaodong Shi +8 more
semanticscholar +1 more source
eLife, 2016 During the development, tight regulation of the expansion of neural progenitor cells (NPCs) and their differentiation into neurons is crucial for normal cortical formation and function.
Wei Zhang +9 more
doaj +1 more source
Review: the development of neural stem cell biology and technology in regenerative medicine [PDF]
arXiv, 2018 In the middle of the last century, it has been known that neural stem cells (NSCs) play a key role in regenerative medicine to cure the neurodegenerative disease. This review article covers about the introduction to neural stem cell biology and the isolation, differentiation and transplantation methods/techniques of neural stem cells.
arxiv
Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells. [PDF]
, 2019 Cell state-, developmental stage-, and lineage-specific combinatorial expression of cluster of differentiation (CD) molecules enables the identification of cellular subsets via multicolor flow cytometry.
Bartos, Marlene +8 more
core +1 more source
The vasculature as a neural stem cell niche [PDF]
Neurobiology of Disease, 2017 Neural stem cells (NSCs) are multipotent, self-renewing progenitors that generate progeny that differentiate into neurons and glia. NSCs in the adult mammalian brain are generally quiescent. Environmental stimuli such as learning or exercise can activate quiescent NSCs, inducing them to proliferate and produce new neurons and glia.
Otsuki, Leo, Brand, Andrea H
openaire +4 more sources
Combination Cell Therapy with Mesenchymal Stem Cells and Neural Stem Cells for Brain Stroke in Rats
International Journal of Stem Cells, 2015 Objectives Brain stroke is the second most important events that lead to disability and morbidity these days. Although, stroke is important, there is no treatment for curing this problem.
S. Hosseini +7 more
semanticscholar +1 more source
Stem Cells, Neural Progenitors, and Engineered Stem Cells [PDF]
, 2014 Human pluripotent stem cells (hPSCs ) have the unique potential to form every cell type in the body. This potential provides opportunities for generating human progenitors and other differentiated cell types for understanding human development and for use in cell type-specific therapies. Equally important is the ability to engineer stem cells and their
Shilpa Iyer, Raj R. Rao
openaire +3 more sources
Annals of Neurology, 2014 The US Food and Drug Administration–approved trial, “A Phase 1, Open‐Label, First‐in‐Human, Feasibility and Safety Study of Human Spinal Cord‐Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis, Protocol Number ...
E. Feldman +9 more
semanticscholar +1 more source
Stem Cells: The Good, the Bad and the Ugly [PDF]
arXiv, 2016 Cancer stem cells are controlled by developmental networks that are often topologically indistinguishable from normal, healthy stem cells. The question is why cancer stem cells can be both phenotypically distinct and have morphological effects so different from normal stem cells.
arxiv