Results 151 to 160 of about 421,776 (345)

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Increased Neurovirulence of Polytropic Mouse Retroviruses Delivered by Inoculation of Brain with Infected Neural Stem Cells

, 1999
David J. Poulsen, Cynthia Favara, Evan Y. Snyder, John L. Portis, Bruce Chesebro   +4 more
openalex   +1 more source

Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro [PDF]

, 2002
Joy Rathjen, Peter D. Rathjen
openalex   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Therapeutic Potential of Neurotrophic Factors and Neural Stem Cells Against Ischemic Brain Injury

, 2000
Koji Abe
openalex   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Transforming Growth Factor β1 Regulates Melanocyte Proliferation and Differentiation in Mouse Neural Crest Cells Via Stem Cell Factor/KIT Signaling [PDF]

, 2002
Tamihiro Kawakami, Yoshinao Soma, Yoko Kawa, Masaru Ito, Emiko Yamasaki, Hidenori Watabe, Eri Hosaka, Kenji Yajima, Kayoko Ohsumi, Masako Mizoguchi   +9 more
openalex   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Properties of a Fetal Multipotent Neural Stem Cell (NEP Cell)

, 2002
Jingli Cai, Yuanyuan Wu, Takumi Mirua, Jeanne L. Pierce, Mary T. Lucero, Kurt H. Albertine, Gerald J. Spangrude, Mahendra S. Rao   +7 more
openalex   +2 more sources

Differentiation and Histological Analysis of Embryonic Stem Cell‐Derived Neural Transplants in Mice

, 2000
Yves Benninger, Silvia Marino, Roland Hardegger, Charles Weissmann, Adriano Aguzzi, Sebastian Brandner   +5 more
openalex   +2 more sources