Results 191 to 200 of about 1,438,323 (398)

Generation of Human Epidermis-Derived Mesenchymal Stem Cell-like Pluripotent Cells and their reprogramming in mouse chimeras [PDF]

open access: yes, 2011
Stem cells can be derived from the embryo (embryonic stem cells, ESCs), from adult tissues (adult stem cells, ASCs), and by induction of fibroblasts (induced pluripotent stem cells, iPSs).
Bing Huang   +21 more
core   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi   +13 more
wiley   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

open access: yesAdvanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell   +5 more
wiley   +1 more source

Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons

open access: yesStem Cell Reports, 2018
Summary: The brain of Down syndrome (DS) patients exhibits fewer interneurons in the cerebral cortex, but its underlying mechanism remains unknown. By morphometric analysis of cortical interneurons generated from DS and euploid induced pluripotent stem ...
Hai-Qin Huo   +10 more
doaj  

Neural differentiation of mouse embryonic stem cells grown in monolayer [PDF]

open access: bronze, 2002
Jiřı́ Pachernı́k   +4 more
openalex   +1 more source

Neural Stem Cell Heterogeneity [PDF]

open access: yes, 2013
The concept of neurogenic neural stem cells in the brains of adult mammals including humans is now widely accepted. In rodents these cells have been studied extensively both in vitro and in vivo. Of the two primary neurogenic regions in the rodent brain, the subventricular zone of the lateral ventricle wall generates the most neurons of multiple ...
openaire   +3 more sources

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

open access: yesAdvanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar   +4 more
wiley   +1 more source

Neural Stem Cells in Primary Central Nervous System Lymphoma [PDF]

open access: yes, 2012
The initial intent of this study was to examine the origins of Primary Central Nervous System Lymphoma (PCNSL), a neoplasm whose oncogenesisin immunocompetentpatients is incompletely understood.
Campbell, Jack   +4 more
core  

Neural Crest Stem Cells Persist in the Adult Gut but Undergo Changes in Self-Renewal, Neuronal Subtype Potential, and Factor Responsiveness [PDF]

open access: bronze, 2002
Genevieve M. Kruger   +5 more
openalex   +1 more source

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