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Transformation of radial glia into postnatal neural stem cells depends on birth. [PDF]

open access: yesCell Rep
Takemura S   +15 more
europepmc   +1 more source

A Human Hippocampal Organoid Model with Sustained Neural Stem Cells Reveals State Shifts Under Glucocorticoid Stress

open access: yes
Soper O   +11 more
europepmc   +1 more source
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Neural Stem Cells

2011
Neural stem/progenitor cell (NPC) cultures are a tool to study the differentiation of neuronal cells and can be used to model disease conditions in studies investigating the pathological mechanisms affecting the development and cellular plasticity of the central nervous system.
Roshan Tofighi   +4 more
  +5 more sources

Hormesis and neural stem cells

Free Radical Biology and Medicine, 2022
This paper provides a detailed identification and assessment of hormetic dose responses in neural stem cells (NSCs) as identified in a number of animal models and human tissues, with particular emphasis on cell proliferation and differentiation. Hormetic dose responses were commonly observed following administration of a number of agents, including ...
Calabrese, Edward J   +4 more
openaire   +3 more sources

Neural Stem Cells

2019
Neural stem cell (NSC) transplantation has provided the basis for the development of potentially powerful new therapeutic cell-based strategies for a broad spectrum of clinical diseases, including stroke, psychiatric illnesses such as fetal alcohol spectrum disorders, and cancer.
Tuazon J. P.   +6 more
openaire   +2 more sources

The neural stem cell niche

Cell and Tissue Research, 2007
The neural stem cell niche defines a zone in which stem cells are retained after embryonic development for the production of new cells of the nervous system. This continual supply of new neurons and glia then provides the postnatal and adult brain with an added capacity for cellular plasticity, albeit one that is restricted to a few specific zones ...
Joanne C, Conover, Ryan Q, Notti
openaire   +2 more sources

Neural stem cell heterogeneity

Progress in Neurobiology, 2018
The ‘identity’ of the neural stem cell (NSC) in the adult mammalian brain has captivated the interest and imagination of scientists since the seminal findings in the 1990s revealing the existence of a unique subset of glial-like cells that fulfill the stem cell criteria of self-renewal and multipotentality.
Jean-Stéphane, Joly, Vincent, Tropepe
openaire   +2 more sources

Proteomics of neural stem cells

Expert Review of Proteomics, 2008
The isolation of neural stem cells from fetal and adult mammalian CNS and the demonstration of functional neurogenesis in adult CNS have offered perspectives for treatment of many devastating hereditary and acquired neurological diseases. Due to this enormous potential, neural stem cells are a subject of extensive molecular profiling studies with a ...
Helena, Skalnikova   +3 more
openaire   +2 more sources

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