Results 61 to 70 of about 1,237,621 (358)
A quantitative system for discriminating induced pluripotent stem cells, embryonic stem cells and somatic cells [PDF]
, 2012 Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) derived from somatic cells (SCs) provide promising resources for regenerative medicine and medical research, leading to a daily identification of new cell lines. However, an efficient system to discriminate the cell lines is lacking.
arxiv +1 more source
Stem cell population asymmetry can reduce rate of replicative aging [PDF]
Journal of Theoretical Biology 331 (2013) 19-27, 2012 Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant flux of differentiated cells. These tissues are maintained by a population of stem cells, which generate differentiated progenies and self-renew. Asymmetric division of each stem cell into one stem cell and one differentiated cell can accomplish both ...
arxiv +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Frontiers in Cell and Developmental Biology, 2022 Stem cells, specifically embryonic stem cells (ESCs), mesenchymal stem cells (MSCs), induced pluripotent stem cells (IPSCs), and neural progenitor stem cells (NSCs), are a possible treatment for stroke, Parkinson’s disease (PD), and Huntington’s disease (
Reed Berlet +4 more
doaj +1 more source
Neural Stem and Progenitor Cells in Nervous System Function and Therapy
Stem Cells International, 2016 For over two decades a significant proportion of neuroscience research has been dedicated to understanding the normal function of neural stem and progenitor cells, as well as developing novel ways to use them to achieve nervous system repair.
T. Walker, Jeffrey K. Huang, K. Young
semanticscholar +1 more source
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Stimulatory effect of icariin on the proliferation of neural stem cells from rat hippocampus
BMC Complementary and Alternative Medicine, 2018 Background Icariin (ICA), a major ingredient of Epimediumbrevicornum, has various pharmacological activities including central nervous system protective functions such as the improvement of learning and memory function in mice models of Alzheimer’s ...
Xiaolong Fu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Two major gate-keepers in the self-renewal of neural stem cells: Erk1/2 and PLCγ1 in FGFR signaling
Molecular Brain, 2009 Neural stem cells are undifferentiated precursor cells that proliferate, self-renew, and give rise to neuronal and glial lineages. Understanding the molecular mechanisms underlying their self-renewal is an important aspect in neural stem cell biology ...
Lee Jin-A +2 more
doaj +1 more source
PLoS ONE, 2016 The dismal success rate of clinical trials for Alzheimer’s disease (AD) motivates us to develop model systems of AD pathology that have higher predictive validity.
W. Raja +6 more
semanticscholar +1 more source