Results 41 to 50 of about 430,196 (291)

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Micro- and nanoengineering approaches to control stem cell-biomaterial interactions. [PDF]

open access: yes, 2011
As our population ages, there is a greater need for a suitable supply of engineered tissues to address a range of debilitating ailments. Stem cell based therapies are envisioned to meet this emerging need. Despite significant progress in controlling stem
Dokmeci, Mehmet R   +4 more
core   +2 more sources

Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy

open access: yesBioengineering
Cell therapy has proven to be a promising treatment for a range of neurological disorders, including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after brain damage.
Ana Gonzalez-Ramos   +3 more
doaj   +1 more source

MiR-7 inhibited peripheral nerve injury repair by affecting neural stem cells migration and proliferation through cdc42

open access: yesMolecular Pain, 2018
Objective Neural stem cells play an important role in the recovery and regeneration of peripheral nerve injury, and the microRNA-7 (miR-7) regulates differentiation of neural stem cells.
Nan Zhou   +7 more
doaj   +1 more source

Roles of neural stem cells in the repair of peripheral nerve injury

open access: yesNeural Regeneration Research, 2017
Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Expression and function of Ndel1 during the differentiation of neural stem cells induced by hippocampal exosomesticle

open access: yesStem Cell Research & Therapy, 2021
Background In the brain of adult mammals, neural stem cells persist in the subventricular zone of the lateral ventricle and the subgranular zone of the dentate gyrus, which are specialized niches with proliferative capacity. Most neural stem cells are in
Wen Li   +8 more
doaj   +1 more source

Cell cycle exit and neuronal differentiation 1-engineered embryonic neural stem cells enhance neuronal differentiation and neurobehavioral recovery after experimental traumatic brain injury

open access: yesNeural Regeneration Research, 2022
Our previous study showed that cell cycle exit and neuronal differentiation 1 (CEND1) may participate in neural stem cell cycle exit and oriented differentiation. However, whether CEND1-transfected neural stem cells can improve the prognosis of traumatic
Ren Wang   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Exogenous Leukemia Inhibitory Factor Stimulates Oligodendrocyte Progenitor Cell Proliferation and Enhances Hippocampal Remyelination [PDF]

open access: yes, 2012
New CNS neurons and glia are generated throughout adulthood from endogenous neural stem and progenitor cells. These progenitors can respond to injury, but their ability to proliferate, migrate, differentiate, and survive is usually insufficient to ...
Deverman, Benjamin E.   +1 more
core   +1 more source

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