Results 41 to 50 of about 6,824,203 (310)

Oscillating field stimulation promotes neurogenesis of neural stem cells through miR-124/Tal1 axis to repair spinal cord injury in rats

open access: yesNeural Regeneration Research, 2023
Spinal cord injury often leads to severe motor and sensory deficits, and prognosis using the currently available therapies remains poor. Therefore, we aimed to explore a novel therapeutic approach for improving the prognosis of spinal cord injury.
Chao Fang   +3 more
doaj   +1 more source

Neural crest-derived stem cells [PDF]

open access: yes, 2010
The neural crest is a transient embryonic structure in vertebrates that gives rise to most of the peripheral nervous system (PNS) and to several non-neural cell types, including smooth muscle cells of the cardiovascular system, pigment cells in the skin,
Sommer, L, Shakhova, O
core   +1 more source

The gut–brain axis: mechanisms linking intestinal dysbiosis with stroke

open access: yesFrontiers in Cell and Developmental Biology
Gut microbiota has emerged as a key regulator of immune, metabolic, and neuroinflammatory processes, exerting significant influence on central nervous system (CNS) function via the gut-brain axis.
José Tomás Garrido Santos   +6 more
doaj   +1 more source

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function.
Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Neural stem cells in Drosophila : molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [PDF]

open access: yes, 2012
Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors.
Heinrich Reichert   +5 more
core   +1 more source

Molecular Fate Determinants in Embryonic and Adult Neural Stem Cells [PDF]

open access: yes, 2005
The molecular signals specifying neuronal, glial or multipotent precursors in the developing and adult central nervous system (CNS) are largely unknown. Radial glial cells have recently been discovered as major precursor population generating neurons or ...
Hack, M.A., Hack, Michael Anton
core   +1 more source

Neural Stem Cells and Stroke

open access: yesCell Transplantation, 2013
Acute ischemic stroke causes a disturbance of neuronal circuitry and disruption of the blood–brain barrier that can lead to functional disabilities. At present, thrombolytic therapy inducing recanalization of the occluded vessels in the cerebral infarcted area is a commonly used therapeutic strategy.
Dah-Ching Ding   +3 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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