Results 21 to 30 of about 230,702 (311)
eLife, 2018 Human GABAergic interneurons (GIN) are implicated in normal brain function and in numerous mental disorders. However, the generation of functional human GIN subtypes from human pluripotent stem cells (hPSCs) has not been established.
Fang Yuan +11 more
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Mathematics, 2020 In this paper, we study the interactions between microglia and neural stem cells and the impact of these interactions on the brain cells during a stroke.
Awatif Jahman Alqarni +2 more
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Transcriptional profiling of adult neural stem-like cells from the human brain. [PDF]
PLoS ONE, 2014 There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of the ...
Cecilie Jonsgar Sandberg +4 more
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Cell Transplantation, 2013 Acute ischemic stroke causes a disturbance of neuronal circuitry and disruption of the blood–brain barrier that can lead to functional disabilities. At present, thrombolytic therapy inducing recanalization of the occluded vessels in the cerebral infarcted area is a commonly used therapeutic strategy.
Dah-Ching Ding +3 more
openaire +3 more sources
Perspective: Of Mice and Men – How Widespread Is Adult Neurogenesis?
Frontiers in Neuroscience, 2019 These are exciting times for research on adult hippocampal neurogenesis (AHN). Debate and controversy regarding the existence of generation of new neurons in the adult, and even diseased human brain flourishes as articles against and in favor accumulate.
David Petrik +5 more
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Characterization of TLX expression in neural stem cells and progenitor cells in adult brains. [PDF]
PLoS ONE, 2012 TLX has been shown to play an important role in regulating the self-renewal and proliferation of neural stem cells in adult brains. However, the cellular distribution of endogenous TLX protein in adult brains remains to be elucidated.
Shengxiu Li +4 more
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Neural Stem Cells Therapy to Treat Neurodegenerative Diseases [PDF]
E3S Web of Conferences, 2021 Neural stem cells have the ability to proliferation, differentiate and renew, which plays an important role in the growth, maturation and senescence of the human brain.
Chen Weibai
doaj +1 more source
HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
Life Science AllianceBlocking epidermal growth factor receptor signaling after seizures prevents the induction of reactive neural stem cells and preserves neurogenesis in the hippocampus of mice.
Oier Pastor-Alonso +7 more
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Neural Regeneration Research, 2015 The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro.
Min-fei Wu +5 more
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Neural Regeneration Research, 2023 Spinal cord injury often leads to severe motor and sensory deficits, and prognosis using the currently available therapies remains poor. Therefore, we aimed to explore a novel therapeutic approach for improving the prognosis of spinal cord injury.
Chao Fang +3 more
doaj +1 more source