Results 21 to 30 of about 218,637 (263)

Transcriptional profiling of adult neural stem-like cells from the human brain. [PDF]

open access: yesPLoS ONE, 2014
There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of the ...
Cecilie Jonsgar Sandberg   +4 more
doaj   +1 more source

The stem cells of the neural crest [PDF]

open access: yesCell Cycle, 2008
In the vertebrate embryo, the neurectodermal neural crest cells (NCC) have remarkably broad potencies, giving rise, after a migratory phase, to neurons and glial cells in the peripheral nervous system, and to skin melanocytes, being all designated here as "neural" derivatives.
Nicole M, Le Douarin   +2 more
openaire   +2 more sources

HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures

open access: yesLife Science Alliance
Blocking epidermal growth factor receptor signaling after seizures prevents the induction of reactive neural stem cells and preserves neurogenesis in the hippocampus of mice.
Oier Pastor-Alonso   +7 more
doaj   +1 more source

Characterization of TLX expression in neural stem cells and progenitor cells in adult brains. [PDF]

open access: yesPLoS ONE, 2012
TLX has been shown to play an important role in regulating the self-renewal and proliferation of neural stem cells in adult brains. However, the cellular distribution of endogenous TLX protein in adult brains remains to be elucidated.
Shengxiu Li   +4 more
doaj   +1 more source

Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord

open access: yesNeural Regeneration Research, 2015
The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro.
Min-fei Wu   +5 more
doaj   +1 more source

Oscillating field stimulation promotes neurogenesis of neural stem cells through miR-124/Tal1 axis to repair spinal cord injury in rats

open access: yesNeural Regeneration Research, 2023
Spinal cord injury often leads to severe motor and sensory deficits, and prognosis using the currently available therapies remains poor. Therefore, we aimed to explore a novel therapeutic approach for improving the prognosis of spinal cord injury.
Chao Fang   +3 more
doaj   +1 more source

Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy

open access: yesBioengineering
Cell therapy has proven to be a promising treatment for a range of neurological disorders, including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after brain damage.
Ana Gonzalez-Ramos   +3 more
doaj   +1 more source

The gut–brain axis: mechanisms linking intestinal dysbiosis with stroke

open access: yesFrontiers in Cell and Developmental Biology
Gut microbiota has emerged as a key regulator of immune, metabolic, and neuroinflammatory processes, exerting significant influence on central nervous system (CNS) function via the gut-brain axis.
José Tomás Garrido Santos   +6 more
doaj   +1 more source

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function.
Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
doaj   +1 more source

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