Results 21 to 30 of about 430,196 (291)

First steps to define murine amniotic fluid stem cell microenvironment [PDF]

open access: yes, 2016
Stem cell niche refers to the microenvironment where stem cells reside in living organisms. Several elements define the niche and regulate stem cell characteristics, such as stromal support cells, gap junctions, soluble factors, extracellular matrix ...
Bertin, Enrica   +11 more
core   +3 more sources

Human Dental Pulp Stem Cells Grown in Neurogenic Media Differentiate Into Endothelial Cells and Promote Neovasculogenesis in the Mouse Brain

open access: yesFrontiers in Physiology, 2019
Dental pulp stem cells (DPSCs) have the capacity to give rise to cells with neuronal-like phenotypes, suggesting their use in brain cell therapies. In the present work, we wanted to address the phenotypic fate of adult genetically unmodified human DPSCs ...
Jon Luzuriaga   +7 more
doaj   +1 more source

The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]

open access: yes, 2005
The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Cederberg, A   +6 more
core   +2 more sources

Fast and Efficient Neural Conversion of Human Hematopoietic Cells

open access: yesStem Cell Reports, 2014
Neurons obtained directly from human somatic cells hold great promise for disease modeling and drug screening. Available protocols rely on overexpression of transcription factors using integrative vectors and are often slow, complex, and inefficient.
Julio Castaño   +14 more
doaj   +1 more source

Induction of human somatostatin and parvalbumin neurons by expressing a single transcription factor LIM homeobox 6

open access: yeseLife, 2018
Human GABAergic interneurons (GIN) are implicated in normal brain function and in numerous mental disorders. However, the generation of functional human GIN subtypes from human pluripotent stem cells (hPSCs) has not been established.
Fang Yuan   +11 more
doaj   +1 more source

Dynamic Modelling of Interactions between Microglia and Endogenous Neural Stem Cells in the Brain during a Stroke

open access: yesMathematics, 2020
In this paper, we study the interactions between microglia and neural stem cells and the impact of these interactions on the brain cells during a stroke.
Awatif Jahman Alqarni   +2 more
doaj   +1 more source

Neural Stem Cells Therapy to Treat Neurodegenerative Diseases [PDF]

open access: yesE3S Web of Conferences, 2021
Neural stem cells have the ability to proliferation, differentiate and renew, which plays an important role in the growth, maturation and senescence of the human brain.
Chen Weibai
doaj   +1 more source

Transcriptional profiling of adult neural stem-like cells from the human brain. [PDF]

open access: yesPLoS ONE, 2014
There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of the ...
Cecilie Jonsgar Sandberg   +4 more
doaj   +1 more source

Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]

open access: yes, 2019
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan   +4 more
core   +2 more sources

Stem Cells, Neural Progenitors, and Engineered Stem Cells [PDF]

open access: yes, 2014
Human pluripotent stem cells (hPSCs ) have the unique potential to form every cell type in the body. This potential provides opportunities for generating human progenitors and other differentiated cell types for understanding human development and for use in cell type-specific therapies. Equally important is the ability to engineer stem cells and their
Raj R, Rao, Shilpa, Iyer
openaire   +2 more sources

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