Transcriptional profiling of adult neural stem-like cells from the human brain. [PDF]
PLoS ONE, 2014 There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of the ...
Cecilie Jonsgar Sandberg +4 more
doaj +1 more source
The stem cells of the neural crest [PDF]
Cell Cycle, 2008 In the vertebrate embryo, the neurectodermal neural crest cells (NCC) have remarkably broad potencies, giving rise, after a migratory phase, to neurons and glial cells in the peripheral nervous system, and to skin melanocytes, being all designated here as "neural" derivatives.
Nicole M, Le Douarin +2 more
openaire +2 more sources
Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies. [PDF]
, 2015 Enteric neural stem cells provide hope of curative treatment for enteric neuropathies. Current protocols for their harvesting from humans focus on the generation of 'neurospheres' from cultures of dissociated gut tissue.
Ellen Binder +45 more
core +2 more sources
HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
Life Science AllianceBlocking epidermal growth factor receptor signaling after seizures prevents the induction of reactive neural stem cells and preserves neurogenesis in the hippocampus of mice.
Oier Pastor-Alonso +7 more
doaj +1 more source
Characterization of TLX expression in neural stem cells and progenitor cells in adult brains. [PDF]
PLoS ONE, 2012 TLX has been shown to play an important role in regulating the self-renewal and proliferation of neural stem cells in adult brains. However, the cellular distribution of endogenous TLX protein in adult brains remains to be elucidated.
Shengxiu Li +4 more
doaj +1 more source
Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation [PDF]
, 2014 The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632) +23 more
core +1 more source
The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]
, 2005 The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Hjerling-Leffler, J +16 more
core +1 more source
Neural Regeneration Research, 2015 The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro.
Min-fei Wu +5 more
doaj +1 more source
A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells [PDF]
, 2014 Neurogenesis is initiated by a set of basic Helix-Loop-Helix (bHLH) transcription factors that specify neural progenitors and allow them to generate neurons in multiple rounds of asymmetric cell division.
Heinrich Reichert +25 more
core +1 more source
Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy
BioengineeringCell therapy has proven to be a promising treatment for a range of neurological disorders, including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after brain damage.
Ana Gonzalez-Ramos +3 more
doaj +1 more source