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Introduction to Neural Stem Cells [PDF]

open access: yesStroke, 2007
Neural stem cells self-renew and give rise to neurons, astrocytes and oligodendrocytes. These cells hold great promise for neural repair after injury or disease. However, a great deal of information needs to be gathered before optimally using neural stem cells for neural repair.
openaire   +2 more sources

Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy

open access: yesBioengineering
Cell therapy has proven to be a promising treatment for a range of neurological disorders, including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after brain damage.
Ana Gonzalez-Ramos   +3 more
doaj   +1 more source

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function.
Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
doaj   +1 more source

The gut–brain axis: mechanisms linking intestinal dysbiosis with stroke

open access: yesFrontiers in Cell and Developmental Biology
Gut microbiota has emerged as a key regulator of immune, metabolic, and neuroinflammatory processes, exerting significant influence on central nervous system (CNS) function via the gut-brain axis.
José Tomás Garrido Santos   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

MiR-7 inhibited peripheral nerve injury repair by affecting neural stem cells migration and proliferation through cdc42

open access: yesMolecular Pain, 2018
Objective Neural stem cells play an important role in the recovery and regeneration of peripheral nerve injury, and the microRNA-7 (miR-7) regulates differentiation of neural stem cells.
Nan Zhou   +7 more
doaj   +1 more source

Roles of neural stem cells in the repair of peripheral nerve injury

open access: yesNeural Regeneration Research, 2017
Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang   +4 more
doaj   +1 more source

Expression and function of Ndel1 during the differentiation of neural stem cells induced by hippocampal exosomesticle

open access: yesStem Cell Research & Therapy, 2021
Background In the brain of adult mammals, neural stem cells persist in the subventricular zone of the lateral ventricle and the subgranular zone of the dentate gyrus, which are specialized niches with proliferative capacity. Most neural stem cells are in
Wen Li   +8 more
doaj   +1 more source

Neural Stem Cells in the Diabetic Brain [PDF]

open access: yesStem Cells International, 2012
Experimental diabetes in rodents rapidly affects the neurogenic niches of the adult brain. Moreover, behavioral disorders suggest that a similar dysfunction of the neurogenic niches most likely affects diabetic and prediabetic patients. Here, we review our present knowledge about adult neural stem cells, the methods used for their study in diabetic ...
Tomás P. Bachor, Ángela M. Suburo
openaire   +4 more sources

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