Results 11 to 20 of about 211,754 (264)

Neural Stem Cells

open access: yesJournal of Investigative Dermatology Symposium Proceedings, 1997
This article is concerned with the idea that neural precursor cells in vertebrates can self-renew and give rise to all cell types within the nervous system. Supportive evidence for this notion of neural stem cells comes from clonal analyses undertaken both in vivo and in vitro. Neural stem cells also give rise to other cells in the body, including skin
Murphy, M   +4 more
openaire   +4 more sources

iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases

open access: yesEMBO Molecular Medicine, 2017
Disease modeling with induced pluripotent stem cells (iPSCs) is creating an abundance of phenotypic information that has become difficult to follow and interpret.
Ethan W Hollingsworth   +9 more
doaj   +1 more source

Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy

open access: yesStem Cells International, 2012
Pluripotent stem cells are regarded as a promising cell source to obtain human dopamine neurons in sufficient amounts and purity for cell replacement therapy.
Julio C. Aguila   +2 more
doaj   +1 more source

Human neural stem cells

open access: yesCell Proliferation, 2023
Abstract‘Human neural stem cells’ jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human neural stem cells (hNSCs) in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packaging requirements ...
Yu‐Kai Wang   +30 more
openaire   +2 more sources

Neural Stem Cells and Glioblastoma [PDF]

open access: yesThe Neuroradiology Journal, 2014
Glioblastoma multiforme represents one of the most common brain cancers with a rather heterogeneous cellular composition, as indicated by the term “multiforme“. Recent reports have described the isolation and identification of cancer neural stem cells from human adult glioblastoma multiforme, which possess the capacity to establish, sustain, and ...
Rossella, Rispoli   +4 more
openaire   +2 more sources

Human Dental Pulp Stem Cells Grown in Neurogenic Media Differentiate Into Endothelial Cells and Promote Neovasculogenesis in the Mouse Brain

open access: yesFrontiers in Physiology, 2019
Dental pulp stem cells (DPSCs) have the capacity to give rise to cells with neuronal-like phenotypes, suggesting their use in brain cell therapies. In the present work, we wanted to address the phenotypic fate of adult genetically unmodified human DPSCs ...
Jon Luzuriaga   +7 more
doaj   +1 more source

Fast and Efficient Neural Conversion of Human Hematopoietic Cells

open access: yesStem Cell Reports, 2014
Neurons obtained directly from human somatic cells hold great promise for disease modeling and drug screening. Available protocols rely on overexpression of transcription factors using integrative vectors and are often slow, complex, and inefficient.
Julio Castaño   +14 more
doaj   +1 more source

Induction of human somatostatin and parvalbumin neurons by expressing a single transcription factor LIM homeobox 6

open access: yeseLife, 2018
Human GABAergic interneurons (GIN) are implicated in normal brain function and in numerous mental disorders. However, the generation of functional human GIN subtypes from human pluripotent stem cells (hPSCs) has not been established.
Fang Yuan   +11 more
doaj   +1 more source

Dynamic Modelling of Interactions between Microglia and Endogenous Neural Stem Cells in the Brain during a Stroke

open access: yesMathematics, 2020
In this paper, we study the interactions between microglia and neural stem cells and the impact of these interactions on the brain cells during a stroke.
Awatif Jahman Alqarni   +2 more
doaj   +1 more source

Transcriptional profiling of adult neural stem-like cells from the human brain. [PDF]

open access: yesPLoS ONE, 2014
There is a great potential for the development of new cell replacement strategies based on adult human neural stem-like cells. However, little is known about the hierarchy of cells and the unique molecular properties of stem- and progenitor cells of the ...
Cecilie Jonsgar Sandberg   +4 more
doaj   +1 more source

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