Results 51 to 60 of about 323,224 (297)

Rhombomere rotation reveals that multiple mechanisms contribute to the segmental pattern of hindbrain neural crest migration [PDF]

, 1994
Hindbrain neural crest cells adjacent to rhombomeres 2 (r2), r4 and r6 migrate in a segmental pattern, toward the first, second and third branchial arches, respectively.
Bronner-Fraser, Marianne, Scherson, Talma, Sechrist, John   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Effect of retinoic acid on neural tube development in chick embryo [PDF]

Journal of Kerman University of Medical Sciences, 1996
retinoic acid is one of the derivatives of vitamin A.it is used for treatment of dermatitis,but it has different teratogenic effects on developing organs depending on the different stages of embryonic life.neural  tube is made of two different parts ...
M Shariati, M Reza zadeh, M Khaksari, M.R Jafari naveh   +3 more
doaj  

Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse [PDF]

, 2013
Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects ...
Copp, AJ, De Castro, SC, Greene, ND, Leung, KY, Savery, D   +4 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Neural Tube Defects in Iraq

مجله كليه طب الكندي, 2013
1. Embryonic Origin of Neural Tube Defects. Insaf Jasim Mahmoud 2. Etiology of Neural Tube Defectss. Ali Abdul Razzak Obed 3. Epidemiology of Neural Tube Defects in Iraq. Mahmood Dhahir Al-Mendalawi 4. Surgical Management of Neural Tube Defects.
Mahmood Dhahir Al-Mendalaw, Insaf Jasim Mahmoud, Ali Abdul Razzak Obed, Laith Thamer Al-Ameri   +3 more
doaj  

Maternal and neonatal serum magnesium concentrations in neural tube defects pregnancies in Gorgan (North of Iran) - A case control study [PDF]

, 2010
Objective: Neural tube defects (NTD) comprise a group of congenital malformations that include spinabifida, anencephaly and encephalocele. Previous studies have reported the embryotoxic and teratogenic effects of Magnesium deficiency in animal models ...
Golalipour, M.J., Mansourian, A.R.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diacylglycerol kinase γ facilitates the proliferation and migration of neural stem cells in the developing neural tube

Acta Biochimica et Biophysica Sinica
In this study, we aim to investigate diacylglycerol kinase (DGK) γ expression in developing neural tubes (NTs) and its effects on neural stem cell (NSC) proliferation and migration.
Cui Huilin, Du Jiazheng, Xie Jianshan, Zhang Jixia, Tao Yun, Huang Yige, Li Lei, Cao Ximei, Zhang Yu   +8 more
doaj   +1 more source

Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia

Journal of Developmental Biology, 2019
The primary cilia play essential roles in Hh-dependent Gli2 activation and Gli3 proteolytic processing in mammals. However, the roles of the cilia in Gli1 activation remain unresolved due to the loss of Gli1 transcription in cilia mutant embryos, and the
Yuan Wang, Huiqing Zeng, Aimin Liu
doaj   +1 more source