Results 31 to 40 of about 323,224 (297)
Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning [PDF]
, 2017 Sonic Hedgehog (Shh) is a ventrally enriched morphogen controlling dorsoventral patterning of the neural tube. In the dorsal spinal cord, Gli3 protein bound to suppressor-of-fused (Sufu) is converted into Gli3 repressor (Gli3R), which inhibits Shh-target
Kawano, Rie +2 more
core +1 more source
Lunatic fringe causes expansion and increased neurogenesis of trunk neural tube and neural crest populations [PDF]
, 2007 Both neurons and glia of the PNS are derived from the neural crest. In this study, we have examined the potential function of lunatic fringe in neural tube and trunk neural crest development by gain-of-function analysis during early stages of nervous ...
Arman, Odette +3 more
core +3 more sources
Molecular and morphogenetic features of neurulation
Zaporožskij Medicinskij ŽurnalNeurulation occurs by two different mechanisms, called primary and secondary neurulation. In humans, primary neurulation occurs along most of the rostrocaudal axis of the embryo, while secondary neurulation occurs caudally, only in the lower sacral and ...
N. M. Nevmerzhytska +5 more
doaj +1 more source
MedEdPORTAL, 2010 This web-based module provides clear, labeled animations of the significant tissues in central nervous system development of the embryo, starting with the completion of neurulation and including neural tube folding and elaboration of the brainstem ...
Donald Lowrie +3 more
doaj +1 more source
International Journal of Africa Nursing Sciences, 2021 Background: Neural tube defects are one of the most common malformations with a worldwide prevalence of 1–3 per1000 live births. They are the result of failure of the neural tube to close during the 21–28 embryonic days and it had multi-factorial ...
Filmawit Aynalem Tesfay +2 more
doaj +1 more source
Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
core +2 more sources
Interdisciplinary Neurosurgery, 2023 Background: Neural tube defects are among the most common congenital anomalies, particularly in developing countries owing to significant folic acid deficiency. Nevertheless, multiple-site open neural tube defects are extremely rare.
Eyerusalem Bergene +3 more
doaj +1 more source
Developmental potential of trunk neural crest cells in the mouse [PDF]
, 1994 The availability of naturally occurring and engineered mutations in mice which affect the neural crest makes the mouse embryo an important experimental system for studying neural crest cell differentiation.
Bronner-Fraser, Marianne +2 more
core
Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity [PDF]
, 2008 In humans, neural tube closure defects occur in 1: 1000 pregnancies. The design of new strategies for the prevention of such common defects would benefit from an improved understanding of the molecular events underlying neurulation. Neural fold elevation
Bradford, DanaKai +5 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source