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Neural tube defects (NTDs) are the most common congenital malformations (CMFs) in developing fetus. The study was done to determine the incidence and clinical profile of NTDs at a tertiary care hospital. The study was done at Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad, from June 2019 to June 2020.
Sowmya Mailaram +4 more
openaire +2 more sources
The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis, originate from a failure of the embryonic neural tube to close. Human NTD are relatively common and both complex and heterogeneous in genetic origin, but the genetic ...
Diana M. Juriloff, Muriel J. Harris
doaj +1 more source
Involvement of deprivation and environmental lead in neural tube defects:a matched case-control study. [PDF]
OBJECTIVE. To analyse the prevalence of neural tube defects in small geographical areas and seek to explain any spatial variations with reference to environmental lead and deprivation. SETTING.
Awwad, Fuad +4 more
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During primary neurulation, the separation of a single-layered ectodermal sheet into the surface ectoderm (SE) and neural tube specifies SE and neural ectoderm (NE) cell fates.
Chiharu Kimura-Yoshida +4 more
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Background Neural tube defects are common group of central nervous system anomalies of complex etiology and major public health importance worldwide. The occurrence of multiple neural tube defects, however, is an extremely rare event and has never been ...
Mestet Yibeltal Shiferaw +5 more
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Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest [PDF]
The neural crest, a transient population of migratory cells, forms the craniofacial skeleton and peripheral nervous system, among other derivatives in vertebrate embryos. The transcriptional repressor Snail2 is thought to be crucial for the epithelial-to-
Bronner-Fraser, Marianne +2 more
core +1 more source
Introduction: Neural tube defects [PDF]
This volume of Neurosurgical Focus covers an array of topics useful to many specialists who care for patients with neural tube defects and related abnormalities. These patients have specific needs at each stage of the lifespan. Today, many individuals with significant developmental abnormalities of the spinal cord are leading full lives.
Shenandoah, Robinson +3 more
openaire +2 more sources
The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice
Shroom3 is an actin-associated regulator of cell morphology that is required for neural tube closure, formation of the lens placode, and gut morphogenesis in mice and has been linked to chronic kidney disease and directional heart looping in humans ...
Debamitra Das +5 more
doaj +1 more source
Myelomeningocele (MMC) is the most common and severe type of spina bifida in which the developing spine and neural tube fail to close during prenatal development.
Hillary E. Swann‐Thomsen +4 more
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Pax3/7 regulates neural tube closure and patterning in a non-vertebrate chordate
Pax3/7 factors play numerous roles in the development of the dorsal nervous system of vertebrates. From specifying neural crest at the neural plate borders, to regulating neural tube closure and patterning of the resulting neural tube.
Kwantae Kim +2 more
doaj +1 more source

