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Journal of Medical Case Reports, 2021 Background Neural tube defects are common group of central nervous system anomalies of complex etiology and major public health importance worldwide. The occurrence of multiple neural tube defects, however, is an extremely rare event and has never been ...
Mestet Yibeltal Shiferaw +5 more
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Abnormal skull findings in neural tube defects [PDF]
, 2009 The human neural tube develops and closes during the third and fourth week after conception and is normally completed by 28 days post-conception. Malformations, knows as neural tube defects, occure, when the normal closure process fails. Several clinical
Cacciatore , Alessandro +9 more
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The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice
Biology Open, 2014 Shroom3 is an actin-associated regulator of cell morphology that is required for neural tube closure, formation of the lens placode, and gut morphogenesis in mice and has been linked to chronic kidney disease and directional heart looping in humans ...
Debamitra Das +5 more
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Brain and Behavior, 2021 Myelomeningocele (MMC) is the most common and severe type of spina bifida in which the developing spine and neural tube fail to close during prenatal development.
Hillary E. Swann‐Thomsen +4 more
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Molecular and morphogenetic features of neurulation
Zaporožskij Medicinskij ŽurnalNeurulation occurs by two different mechanisms, called primary and secondary neurulation. In humans, primary neurulation occurs along most of the rostrocaudal axis of the embryo, while secondary neurulation occurs caudally, only in the lower sacral and ...
N. M. Nevmerzhytska +5 more
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Inositol, neural tube closure and the prevention of neural tube defects
Birth Defects Research, 2017 Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition. Maternal periconceptional supplementation with folic acid significantly reduces the risk of an NTD‐affected pregnancy, but does not prevent all NTDs, and “folic acid non‐responsive” NTDs ...
Greene, ND, Leung, KY, Copp, AJ
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Role of miRNAs in neural tube development
, 2013 Although mutations in hundreds (>200) of genes have been causally linked to neural tube defects (NTDs) in mouse, in humans the elucidation of genetic factors associated to NTD has remained elusive.
A. Gallina +7 more
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MedEdPORTAL, 2010 This web-based module provides clear, labeled animations of the significant tissues in central nervous system development of the embryo, starting with the completion of neurulation and including neural tube folding and elaboration of the brainstem ...
Donald Lowrie +3 more
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International Journal of Africa Nursing Sciences, 2021 Background: Neural tube defects are one of the most common malformations with a worldwide prevalence of 1–3 per1000 live births. They are the result of failure of the neural tube to close during the 21–28 embryonic days and it had multi-factorial ...
Filmawit Aynalem Tesfay +2 more
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Interdisciplinary Neurosurgery, 2023 Background: Neural tube defects are among the most common congenital anomalies, particularly in developing countries owing to significant folic acid deficiency. Nevertheless, multiple-site open neural tube defects are extremely rare.
Eyerusalem Bergene +3 more
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