Results 21 to 30 of about 323,224 (297)

Neural tube defects

open access: yesMRIMS Journal of Health Sciences, 2021
Neural tube defects (NTDs) are the most common congenital malformations (CMFs) in developing fetus. The study was done to determine the incidence and clinical profile of NTDs at a tertiary care hospital. The study was done at Malla Reddy Institute of Medical Sciences, Suraram, Hyderabad, from June 2019 to June 2020.
Sowmya Mailaram   +4 more
openaire   +2 more sources

Insights into the Etiology of Mammalian Neural Tube Closure Defects from Developmental, Genetic and Evolutionary Studies

open access: yesJournal of Developmental Biology, 2018
The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis, originate from a failure of the embryonic neural tube to close. Human NTD are relatively common and both complex and heterogeneous in genetic origin, but the genetic ...
Diana M. Juriloff, Muriel J. Harris
doaj   +1 more source

Involvement of deprivation and environmental lead in neural tube defects:a matched case-control study. [PDF]

open access: yes, 2009
OBJECTIVE. To analyse the prevalence of neural tube defects in small geographical areas and seek to explain any spatial variations with reference to environmental lead and deprivation. SETTING.
Awwad, Fuad   +4 more
core   +1 more source

Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure

open access: yesEBioMedicine, 2015
During primary neurulation, the separation of a single-layered ectodermal sheet into the surface ectoderm (SE) and neural tube specifies SE and neural ectoderm (NE) cell fates.
Chiharu Kimura-Yoshida   +4 more
doaj   +1 more source

Multiple site neural tube defects at Zewuditu Memorial Hospital, Addis Ababa, Ethiopia: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Neural tube defects are common group of central nervous system anomalies of complex etiology and major public health importance worldwide. The occurrence of multiple neural tube defects, however, is an extremely rare event and has never been ...
Mestet Yibeltal Shiferaw   +5 more
doaj   +1 more source

Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest [PDF]

open access: yes, 2007
The neural crest, a transient population of migratory cells, forms the craniofacial skeleton and peripheral nervous system, among other derivatives in vertebrate embryos. The transcriptional repressor Snail2 is thought to be crucial for the epithelial-to-
Bronner-Fraser, Marianne   +2 more
core   +1 more source

Introduction: Neural tube defects [PDF]

open access: yesNeurosurgical Focus, 2012
This volume of Neurosurgical Focus covers an array of topics useful to many specialists who care for patients with neural tube defects and related abnormalities. These patients have specific needs at each stage of the lifespan. Today, many individuals with significant developmental abnormalities of the spinal cord are leading full lives.
Shenandoah, Robinson   +3 more
openaire   +2 more sources

The interaction between Shroom3 and Rho-kinase is required for neural tube morphogenesis in mice

open access: yesBiology Open, 2014
Shroom3 is an actin-associated regulator of cell morphology that is required for neural tube closure, formation of the lens placode, and gut morphogenesis in mice and has been linked to chronic kidney disease and directional heart looping in humans ...
Debamitra Das   +5 more
doaj   +1 more source

A preliminary investigation of high retinoic acid exposure during fetal development on behavioral competency and litter characteristics in newborn rats

open access: yesBrain and Behavior, 2021
Myelomeningocele (MMC) is the most common and severe type of spina bifida in which the developing spine and neural tube fail to close during prenatal development.
Hillary E. Swann‐Thomsen   +4 more
doaj   +1 more source

Pax3/7 regulates neural tube closure and patterning in a non-vertebrate chordate

open access: yesFrontiers in Cell and Developmental Biology, 2022
Pax3/7 factors play numerous roles in the development of the dorsal nervous system of vertebrates. From specifying neural crest at the neural plate borders, to regulating neural tube closure and patterning of the resulting neural tube.
Kwantae Kim   +2 more
doaj   +1 more source

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