Results 11 to 20 of about 1,866,573 (308)
The Enigmatic Reissner’s Fiber and the Origin of Chordates
Reissner’s fiber (RF) is a secreted filament that floats in the neural canal of chordates. Since its discovery in 1860, there has been no agreement on its primary function, and its strong conservation across chordate species has remained a mystery for ...
Francisco Aboitiz +2 more
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Introduction Neural tube defect is one of the top five most serious birth defects in the world. In Ethiopia an accurate estimate of the trend and burden of neural tube defects is still unknown.
Anteneh Berhane, Tefera Belachew
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Collective behavior and self-organization in neural rosette morphogenesis
Neural rosettes develop from the self-organization of differentiating human pluripotent stem cells. This process mimics the emergence of the embryonic central nervous system primordium, i.e., the neural tube, whose formation is under close investigation ...
Mattia Miotto +16 more
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In vertebrates, the development of the central nervous system depends on the correct patterning of the neural tube along its anterior-posterior and dorsal-ventral axes in the early embryo as well as the underlying regulation of the cell differentiation ...
LIU Cong, XU Pengfei
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A quest for genetic causes underlying signaling pathways associated with neural tube defects
Neural tube defects (NTDs) are serious congenital deformities of the nervous system that occur owing to the failure of normal neural tube closures. Genetic and non-genetic factors contribute to the etiology of neural tube defects in humans, indicating ...
Sunil Rai +4 more
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Members of the Eph receptor tyrosine kinase have previously been implicated in cranial neural tube development. Failure of neural tube closure leads to the devastating conditions known as anencephaly and spina bifida. EphA2 and EphA4 are expressed at the
Nor Linda Abdullah +3 more
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Scratch2, a Snail Superfamily Member, Is Regulated by miR-125b
Scratch2 is a transcription factor expressed in a very restricted population of vertebrate embryonic neural cell precursors involved in their survival, differentiation, and migration.
Carolina Purcell Goes +5 more
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Hedgehog: A Key Signaling in the Development of the Oligodendrocyte Lineage
The Hedgehog morphogen aroused an enormous interest since it was characterized as an essential signal for ventral patterning of the spinal cord two decades ago.
Elisabeth Traiffort +3 more
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The human neural tube defects (NTD), anencephaly, spina bifida and craniorachischisis, originate from a failure of the embryonic neural tube to close. Human NTD are relatively common and both complex and heterogeneous in genetic origin, but the genetic ...
Diana M. Juriloff, Muriel J. Harris
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Pax3/7 regulates neural tube closure and patterning in a non-vertebrate chordate
Pax3/7 factors play numerous roles in the development of the dorsal nervous system of vertebrates. From specifying neural crest at the neural plate borders, to regulating neural tube closure and patterning of the resulting neural tube.
Kwantae Kim +2 more
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