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Pediatric Neurology Briefs, 1988 In an overview of neural tube defects (NTD’s), Dr RJ Lemire of the Dept Pediatrics, Univ of Washington and Children’s Hospital, Seattle, WA, divides them into two major groups: (1) neurulation and (2) postneurulation defects.
J Gordon Millichap
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Curationis, 1981 Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost
M.E. Marshall
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Folic acid supplementation and neural tube defects: a cross-sectional study of knowledge and practice among pregnant mothers in Lira, Northern Uganda [PDF]
BMC Pregnancy and ChildbirthBackground and aim Folic acid requirements increase during pregnancy to meet the metabolic needs, DNA synthesis, and rapid cell division during fetal development.
Rebecca Nakaziba, Miriam Muhindo
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Canadian Medical Association Journal, 2005 The population-based study of neural tube defects by Joel Ray and associates[1][1] raises 2 important concerns. First, as noted by the authors in their discussion of study limitations, ethnicity may simply be a confounding factor in neural tube defects caused by poor folic acid intake. Second,
Fu-Lin, Wang +2 more
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PLoS ONE, 2022 Introduction Neural tube defect is one of the top five most serious birth defects in the world. In Ethiopia an accurate estimate of the trend and burden of neural tube defects is still unknown.
Anteneh Berhane, Tefera Belachew
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Annual Review of Neuroscience, 2014 Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely. Human NTDs are multifactorial, with contributions from both genetic and environmental factors. The genetic basis is not yet well understood,
Greene, ND, Copp, AJ
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Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development
Frontiers in Cell and Developmental Biology, 2023 Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Neophytos Christodoulou +1 more
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A quest for genetic causes underlying signaling pathways associated with neural tube defects
Frontiers in Pediatrics, 2023 Neural tube defects (NTDs) are serious congenital deformities of the nervous system that occur owing to the failure of normal neural tube closures. Genetic and non-genetic factors contribute to the etiology of neural tube defects in humans, indicating ...
Sunil Rai +4 more
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Interdisciplinary Neurosurgery, 2023 Background: Neural tube defects are among the most common congenital anomalies, particularly in developing countries owing to significant folic acid deficiency. Nevertheless, multiple-site open neural tube defects are extremely rare.
Eyerusalem Bergene +3 more
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Junctional Neural Tube Defect [PDF]
Journal of Korean Neurosurgical Society, 2020 Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube ...
Sebastian Eibach, Dachling Pang
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