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, 2013 Neural tube defects consist of anencephaly, encephalocele, and spina bifida. The first two conditions are nowadays rare among infants born (n=35 and 49, respectively). An increased risk for spina bifida (n=312) is seen at high maternal BMI and at non-cohabitation, perhaps due to problems in prenatal diagnosis.
Richard H. Finnell +2 more
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Canadian Medical Association Journal, 2005 The population-based study of neural tube defects by Joel Ray and associates[1][1] raises 2 important concerns. First, as noted by the authors in their discussion of study limitations, ethnicity may simply be a confounding factor in neural tube defects caused by poor folic acid intake. Second,
Hude Quan +2 more
+18 more sources
JAMA: The Journal of the American Medical Association, 1988 Neural tube defects (NTDs) are a group of malformations of the brain and spinal cord that originate at various times during gestation. The most common NTDs are anencephaly and meningomyelocele, which arise during the process of neurulation, a well-defined period between the 17th and 30th day after ovulation.
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Annual Review of Neuroscience, 2014 Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth defects of the central nervous system that originate during embryonic development when the neural tube fails to close completely. Human NTDs are multifactorial, with contributions from both genetic and environmental factors. The genetic basis is not yet well understood,
Greene, ND, Copp, AJ
openaire +4 more sources
Curationis, 1981 Neural tube defects refer to any defect in the morphogenesis of the neural tube, the most common types being spina bifida and anencephaly. Spina bifida has been recognised in skeletons found in north-eastern Morocco and estimated to have an age of almost 12 000 years.
P.H. Jongbloet, N.C. Nevin
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Junctional Neural Tube Defect [PDF]
Journal of Korean Neurosurgical Society, 2020 Junctional neurulation represents the most recent adjunct to the well-known sequential embryological processes of primary and secondary neurulation. While its exact molecular processes, occurring at the end of primary and the beginning of secondary neurulation, are still being actively investigated, its pathological counterpart -junctional neural tube ...
Sebastian Eibach, Dachling Pang
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Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]
, 1981 We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith +18 more
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Magnitude and Associated Factors of Neural Tube Defects in Ethiopia: A Systematic Review and Meta-Analysis. [PDF]
, 2021 Neural tube defects remain a major problem in developing countries, but there are limited comprehensive national reports to date in Ethiopia. Therefore, this study aimed to assess the prevalence of neural tube defects and associated factors in Ethiopia ...
Alebel, A, Alemu, A, Bitew, ZW, Worku, T
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Genetics of human neural tube defects [PDF]
, 2009 Neural tube defects (NTDs) are common, severe congenital malformations whose causation involves multiple genes and environmental factors. Although more than 200 genes are known to cause NTDs in mice, there has been rather limited progress in delineating ...
A. J. Copp +131 more
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Involvement of deprivation and environmental lead in neural tube defects:a matched case-control study. [PDF]
, 2009 OBJECTIVE. To analyse the prevalence of neural tube defects in small geographical areas and seek to explain any spatial variations with reference to environmental lead and deprivation. SETTING.
Awwad, Fuad +4 more
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