Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse [PDF]
Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects ...
Copp, AJ+4 more
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EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2013. Scientific Opinion on the substantiation of a health claim related to increasing maternal folate status by supplemental folate intake and reduced risk of neural tube defects pursuant to Article 14 of Regulation (EC) No 1924/2006 [PDF]
Following an application from Rank Nutrition Ltd, submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of the United Kingdom, the EFSA Panel on Dietetic Products, Nutrition and ...
Czeizel+11 more
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Birth prevalence of neural tube defects and orofacial clefts in India: a systematic review and meta-analysis. [PDF]
BACKGROUND: In the last two decades, India has witnessed a substantial decrease in infant mortality attributed to infectious disease and malnutrition. However, the mortality attributed to birth defects remains constant. Studies on the prevalence of birth
Allagh, Komal Preet+7 more
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Neural tube defects: recent advances, unsolved questions, and controversies [PDF]
Neural tube defects are severe congenital malformations affecting around one in every 1000 pregnancies. An innovation in clinical management has come from the finding that closure of open spina bifida lesions in utero can diminish neurological ...
Copp, AJ, Greene, NDE, Stanier, P
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Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity [PDF]
In humans, neural tube closure defects occur in 1: 1000 pregnancies. The design of new strategies for the prevention of such common defects would benefit from an improved understanding of the molecular events underlying neurulation. Neural fold elevation
Bradford, DanaKai+5 more
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Inositol, neural tube closure and the prevention of neural tube defects [PDF]
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition.
Copp, AJ, Greene, ND, Leung, KY
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Neural tube closure: cellular, molecular and biomechanical mechanisms. [PDF]
Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the severe congenital malformations - 'neural tube defects' - that result ...
Copp, AJ+4 more
core +2 more sources
Lack of serologic evidence for an association between Cache Valley Virus infection and anencephaly and other neural tube defects in Texas. [PDF]
We tested the hypothesis that Cache Valley Virus (CVV), an endemic North American bunyavirus, may be involved in the pathogenesis of human neural tube defects. This investigation followed a 1990 and 1991 south Texas outbreak of neural tube defects with a
Edwards, J. F., Hendricks, K.
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Magnetic resonance imaging in the prenatal diagnosis of neural tube defects [PDF]
OBJECTIVE: To assess the role of magnetic resonance imaging (MRI) in the prenatal diagnosis of neural tube defects (NTDs). BACKGROUND: NTDs comprise a heterogeneous group of congenital anomalies that derive from the failure of the neural tube to close ...
A. Zugazaga Cortazar+4 more
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Incidence and Trends of Neural Tube Defects in Babies Delivered at Dera Ghazi Khan Tertiary Care Center [PDF]
Objective: A cross-section study was conducted to determine the incidence and trends of neural tube defects in babies delivered at a tertiary care center. And those babies who were delivered elsewhere and were brought to a tertiary care center
Asif Qureshi, Muhammad+1 more
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