Results 21 to 30 of about 131,684 (338)

Global analysis of cell behavior and protein dynamics reveals region-specific roles for Shroom3 and N-cadherin during neural tube closure

open access: yeseLife, 2022
Failures of neural tube closure are common and serious birth defects, yet we have a poor understanding of the interaction of genetics and cell biology during neural tube closure.
Austin T Baldwin   +3 more
doaj   +1 more source

Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse [PDF]

open access: yes, 2013
Closure of the neural tube during embryogenesis is a crucial step in development of the central nervous system. Failure of this process results in neural tube defects, including spina bifida and anencephaly, which are among the most common birth defects ...
Copp, AJ   +4 more
core   +1 more source

Involvement of deprivation and environmental lead in neural tube defects:a matched case-control study. [PDF]

open access: yes, 2009
OBJECTIVE. To analyse the prevalence of neural tube defects in small geographical areas and seek to explain any spatial variations with reference to environmental lead and deprivation. SETTING.
Awwad, Fuad   +4 more
core   +1 more source

A case report of triple neural tube defect: revisiting the multisite closure theory

open access: yesBMC Surgery, 2019
Background Triple neural tube defects are rare. To the author’s knowledge, there are only four reported cases available in the literature up to date. Controversies exist with regards to the development of neural tube defects.
Jayant Kumar Yadav   +4 more
doaj   +1 more source

Neogenin and RGMa control neural tube closure and neuroepithelial morphology by regulating cell polarity [PDF]

open access: yes, 2008
In humans, neural tube closure defects occur in 1: 1000 pregnancies. The design of new strategies for the prevention of such common defects would benefit from an improved understanding of the molecular events underlying neurulation. Neural fold elevation
Bradford, DanaKai   +5 more
core   +1 more source

Magnitude and Associated Factors of Neural Tube Defects in Ethiopia: A Systematic Review and Meta-Analysis

open access: yesGlobal Pediatric Health, 2020
Neural tube defects remain a major problem in developing countries, but there are limited comprehensive national reports to date in Ethiopia. Therefore, this study aimed to assess the prevalence of neural tube defects and associated factors in Ethiopia ...
Zebenay Workneh Bitew MSc, MPH   +3 more
doaj   +1 more source

Complex Nature of Neural Tube Defects: A Regional Experience

open access: yesGynecology Obstetrics & Reproductive Medicine, 2018
Objective: The underlying gene-environment interaction of fetal neural tube defects is affected by several factors including geography, ethnicity and time. Local features of fetal neural tube defects were described.
Emrah Turhan   +3 more
doaj   +1 more source

Inositol, neural tube closure and the prevention of neural tube defects [PDF]

open access: yes, 2016
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition.
Copp, AJ, Greene, ND, Leung, KY
core   +1 more source

Neural tube defects: current view on etiology, prenatal prevention, and early diagnosis. A review

open access: yesConsilium Medicum, 2023
A literature review on the etiology, prevention, and early diagnosis of neural tube defects is presented, focusing on the causes and risk factors for these disorders.
Liliyana A. Chugunova   +2 more
doaj   +1 more source

Neural tube defects: recent advances, unsolved questions, and controversies [PDF]

open access: yes, 2013
Neural tube defects are severe congenital malformations affecting around one in every 1000 pregnancies. An innovation in clinical management has come from the finding that closure of open spina bifida lesions in utero can diminish neurological ...
Copp, AJ, Greene, NDE, Stanier, P
core   +1 more source

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