We tested the hypothesis that Cache Valley Virus (CVV), an endemic North American bunyavirus, may be involved in the pathogenesis of human neural tube defects. This investigation followed a 1990 and 1991 south Texas outbreak of neural tube defects with a
J. F. Edwards, K. Hendricks
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Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis. [PDF]
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Hao, Hongyan +4 more
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Association of retinoic acid receptor genes with meningomyelocele. [PDF]
BACKGROUND: Neural tube defects (NTDs) occur in as many as 0.5-2 per 1000 live births in the United States. One of the most common and severe neural tube defects is meningomyelocele (MM) resulting from failed closure of the caudal end of the neural tube.
Au, Kit Sing +6 more
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Maternal serum zinc deficiency in cases of neural tube defect in Gorgan, north Islamic Republic of Iran [PDF]
Previous studies have shown a high rate of neural tube defects (NTD) in Gorgan, northern Islamic Republic of Iran. This case-control study during 2003-04 compared serum zinc levels and other variables in 23 mothers of neonates affected with NTD and 36 ...
Golalipour, M.J. +3 more
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Neural tube closure: cellular, molecular and biomechanical mechanisms. [PDF]
Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the severe congenital malformations - 'neural tube defects' - that result ...
Copp, AJ +4 more
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Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns [PDF]
Folate is vital for fetal development. Periconceptional folic acid supplementation and food fortification are recommended to prevent neural tube defects.
Beckett, E. (Emma) +28 more
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Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear [PDF]
An early and crucial event in vertebrate inner ear development is the acquisition of axial identities that in turn dictate the positions of all subsequent inner ear components.
Bok, Jinwoong +2 more
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Factors Associated with Neural Tube Defects of Neonates in Al-Najaf Government
Objective: To identify the association of neural tube defects with some possible risk factors in Iraqi neonates. Methodology: This is a hospital based case control study carried out in two major hospitals in AL Najaf province during the period (first ...
Narjs A. Hassan, Hassan A. Baee
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Maternal and neonatal serum magnesium concentrations in neural tube defects pregnancies in Gorgan (North of Iran) - A case control study [PDF]
Objective: Neural tube defects (NTD) comprise a group of congenital malformations that include spinabifida, anencephaly and encephalocele. Previous studies have reported the embryotoxic and teratogenic effects of Magnesium deficiency in animal models ...
Golalipour, M.J., Mansourian, A.R.
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