Results 111 to 120 of about 12,096 (222)

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science
Neural tube defects (NTDs) are one of the most common congenital malformations. Folic acid deficiency in pregnant women increases the risk of developing NTDs; however, the underlying etiology and mechanisms remain elusive.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
doaj   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science
Neural tube defects (NTDs) are complex multigenic disorders and are the most prevalent and severe congenital malformations that affect the central nervous system.
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
doaj   +1 more source

Maternal and neonatal serum magnesium concentrations in neural tube defects pregnancies in Gorgan (North of Iran) - A case control study [PDF]

, 2010
Objective: Neural tube defects (NTD) comprise a group of congenital malformations that include spinabifida, anencephaly and encephalocele. Previous studies have reported the embryotoxic and teratogenic effects of Magnesium deficiency in animal models ...
Golalipour, M.J., Mansourian, A.R.
core  

Genomic DNA hypomethylation is associated with neural tube defects induced by methotrexate inhibition of folate metabolism.

PLoS ONE, 2015
DNA methylation is thought to be involved in the etiology of neural tube defects (NTDs). However, the exact mechanism between DNA methylation and NTDs remains unclear.
Xiuwei Wang, Zhen Guan, Yan Chen, Yanting Dong, Yuhu Niu, Jianhua Wang, Ting Zhang, Bo Niu   +7 more
doaj   +1 more source

Folate Deficiency and Prevalence of Neural Tube Defects [NTDs] in Georgia [PDF]

International Journal of Clinical Nutrition & Dietetics, 2019
Robizon Tsiklauri, P. Imnadze, L. Jijeishvili, J. Saganelidze   +3 more
openaire   +1 more source

Association of Lead in Maternal Serum with Fetal Neural Tube Defects (NTDs)

Scholars International Journal of Obstetrics and Gynecology, 2021
  Dr. Fahmida Bayes Kakan, Dr. Firoza Begum, Dr. Nahreen Akhtar, Shamshad Begum Quraisi, Dr. Tabassum Perveen, Dr. Mst. Tajmira Sultana, Dr. Mohammad Saifullah Ahtesam   +6 more
openaire   +1 more source

ApoM maintains cellular homeostasis between mitophagy and apoptosis by affecting the stability of Nnt mRNA through the Zic3-ApoM-Elavl2-Nnt axis during neural tube closure

Cell Death and Disease
Research on the aetiology of neural tube defects (NTDs) has made progress in recent years. However, the molecular mechanism of apolipoproteins underlying NTDs development remains unclear.
Qing Liu, Dan Liu, Yuejiao Wang, Xiaowei Wei, Wei Ma, Hui Gu, Shanshan Jia, Yiwen He, Wenting Luo, Songying Cao, Zhonghua Yang, Anhua Wu, Zhengwei Yuan   +12 more
doaj   +1 more source

Neural tube defects (NTDs) rates, 1995-1999 [PDF]

Teratology, 2002
openaire   +2 more sources

Epidemiology of neural tube defects in northern Iran, 1998-2003 [PDF]

, 2007
We determined the rates of neural tube defects at a referral hospital in Gorgan, north Islamic Republic of Iran, and the relations of these abnormalities to sex, maternal ethnicity, maternal age and season.
Golalipour, M.J., Keshtkar, A.A., Mobasheri, E., Vakili, M.A.   +3 more
core  

Assessment of the Intake and Knowledge of Folate/Folic Acid Among UNH Students [PDF]

, 2017
There are 3,000 U.S. pregnancies affected by spina bifida and anencephaly annually. If women consume adequate amounts of folic acid (400 mcg/day) one month before pregnancy and through the first trimester, then the risk of their infant developing a ...
Bigornia, Sherman, Pelletier, Jessica Lee, Reilly, Ruth   +2 more
core   +2 more sources