Results 71 to 80 of about 155,597 (349)

Primary care incidence and treatment of four neuropathic pain conditions: A descriptive study, 2002–2005

BMC Family Practice, 2008
Background Between 1992 and 2001 the UK general practice incidence of post-herpetic neuralgia and trigeminal neuralgia declined, whilst the incidence of painful diabetic neuropathy increased. The most common first line treatments were compound analgesics.
Carroll Dawn, Hall Gillian C, McQuay Henry J   +2 more
doaj   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Accommodation to Diagnosis of Trigeminal Neuralgia

Acta Clinica Croatica, 2017
Trigeminal neuralgia is one of the most common causes of facial pain. It implies short lasting episodes of unilateral electric shock-like pain with abrupt onset and termination, in the distribution of one or more divisions of the trigeminal nerve that ...
Vanja Bašić Kes, Lucija Zadro Matovina
doaj   +1 more source

A Systematic Review on Cannabinoids for Neuropathic Pain Administered by Routes Other than Oral or Inhalation

Plants, 2022
The use of cannabis and cannabinoid products for the treatment of neuropathic pain is a growing area of research. This type of pain has a high prevalence, limited response to available therapies and high social and economic costs.
Jose-Manuel Quintero, German Pulido, Luis-Fernando Giraldo, Marta-Ximena Leon, Luis-Eduardo Diaz, Rosa-Helena Bustos   +5 more
doaj   +1 more source

Shoulder pain due to cervical radiculopathy: an underestimated long-term complication of herpes zoster virus reactivation? [PDF]

, 2018
Purpose To evaluate if herpes zoster virus (HZV) reactivation may be considered in the aetiology of cervical radiculopathy. Methods The study group was composed of 110 patients (52 M-58F;mean age ± SD:46.5 ± 6.12; range:40-73) with a clinical ...
AS Hilibrand, B Kuijper, Ciro Villani, DA Perez-Martienz, Daniele Passaretti, DH Gilden, E Viikari-Juntura, H Sandmark, HC Tong, I Steiner, JP Makela, K Radhakrishnan, KC Shah, KM Abbed, MC Sanchez, MM Ban Le, MM Vargo, MT Modic, MT Modic, NA Peterslund, PG Kennedy, PW Detwiler, R Atkinson, RE Yoss, RS Wainner, RW Johnson, S Gumina, S Shabat, Stefano Gumina, T Fujy, Vittorio Candela, W Frobin, W Frobin, W Frobin, Y Uematsu   +34 more
core   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus

Frontiers in Integrative Neuroscience, 2018
Herpes zoster or shingles is the result of varicella zoster virus (VZV) infection and often results in chronic pain that lasts for months after visible symptoms subside. Testosterone often attenuates pain in males.
Phillip R. Kramer, Mahesh Rao, Crystal Stinson, Larry L. Bellinger, Paul R. Kinchington, Michael B. Yee   +5 more
doaj   +1 more source

Evaluation of the serum level of estrogen, progesterone, prolactin, and testosterone in patients with trigeminal neuralgia compared to a healthy population

Clinical and Experimental Dental Research, 2023
Objectives The goal of this study is to measure and compare the hormonal serum levels (estrogen, progesterone, testosterone, prolactin, dihydrotestosterone [DHT]) in trigeminal neuroglia (TN) menopausal women and healthy women. Materials and Methods This
Fatemeh Lavaee, Sahar Didar, Aylar Afshari   +2 more
doaj   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

British Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin, Ye Wang, Chao Hu, Yanhuan Feng, Xi Tang, Ping Fu, Jia Miao   +6 more
wiley   +1 more source

Construction of risk prediction model for postherpetic neuralgia of patients with herpes zoster

Huli yanjiu, 2022
ObjectiveTo analyze the risk factors of postherpetic neuralgia（PHN） of patients with herpes zoster and to construct risk prediction model.Methods425 patients with herpes zoster admitted to department of dermatology of our hospital were selected as study ...
LI Jiao, HUANG Guohui, NI Ping
doaj