Results 111 to 120 of about 76,244 (290)

Establishing neuronal identity in vertebrate neurogenic placodes [PDF]

, 2000
The trigeminal and epibranchial placodes of vertebrate embryos form different types of sensory neurons. The trigeminal placodes form cutaneous sensory neurons that innervate the face and jaws, while the epibranchial placodes (geniculate, petrosal and ...
Baker, Clare V. H., Bronner-Fraser, Marianne   +1 more
core  

Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. [PDF]

, 2018
Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs). Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of each RGC type are restricted to specific sublaminae ...
Chen, Bin, Krishnaswamy, Arjun, Laboulaye, Mallory A, Liu, Jinyue, Pandey, Shristi, Reggiani, Jasmine DS, Rubenstein, John LR, Sanes, Joshua R   +7 more
core   +1 more source

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection

mBio
The highly prevalent herpes simplex virus type 1 (HSV-1) causes a range of diseases, including cold sores, blinding keratitis, and life-threatening encephalitis.
Guorong Sun, Kai Alexander Kropp, Marieluise Kirchner, Nina Plückebaum, Anton Selich, Manutea Serrero, Akshay Dhingra, Jorge Rubén Cabrera, Birgit Ritter, Rudolf Bauerfeind, Emanuel Wyler, Markus Landthaler, Axel Schambach, Beate Sodeik, Philipp Mertins, Abel Viejo-Borbolla   +15 more
doaj   +1 more source

Automated Screening of Neurite Outgrowth

SLAS Discovery, 2003
Outgrowth of neurites in culture is used for assessing neurotrophic activity. Neurite measurements have been performed very slowly using manual methods or more efficiently with interactive image analysis systems. In contrast, medium-throughput and noninteractive image analysis of neurite screens has not been well described.
Peter, Ramm, Yuriy, Alexandrov, Andrzej, Cholewinski, Yuriy, Cybuch, Robert, Nadon, Bohdan J, Soltys   +5 more
openaire   +2 more sources

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

The Schwann Cell

Acta Biológica Colombiana, 2004
The neurones are the cells of the nervous system and are surrounded and protected by glials cells. In the peripheral nervous system the Schwann cells (SC) are the glia of the nerves.
Sandra Perdomo, Clara Spinel
doaj  

Nanotopographic control of actin waves and growth cone navigation in developing neurons

Frontiers in Cell and Developmental Biology
The development of axons and dendrites (neurites) in a neural circuit relies on the dynamic interplay of cytoskeletal components, especially actin, and the integration of diverse environmental cues.
Spandan Pathak, Kate M. O’Neill, Emily K. Robinson, Matt J. Hourwitz, Corey Herr, John T. Fourkas, Edward Giniger, Wolfgang Losert, Wolfgang Losert   +8 more
doaj   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites

eLife, 2014
Microtubule dynamics facilitate neurite growth and establish morphology, but the role of minus-end binding proteins in these processes is largely unexplored.
Jana Dorfman Marcette, Jessica Jie Chen, Michael L Nonet   +2 more
doaj   +1 more source