Results 61 to 70 of about 56,568 (206)

Interactions between growth cones and neurites growing from different neural tissues in culture

, 1987
We have previously used retinal and sympathetic explants to show that growth cones recognize and retract from specific neurites in culture (Kapfhammer et al., 1986).
JP Kapfhammer, Kapfhammer, J. ; https://orcid.org/, JA Raper, Raper, J.   +3 more
core   +1 more source

Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells

eLife
Autism spectrum disorder (ASD) is defined by common behavioral characteristics, raising the possibility of shared pathogenic mechanisms. Yet, vast clinical and etiological heterogeneity suggests personalized phenotypes.
Smrithi Prem, Bharati Dev, Cynthia Peng, Monal Mehta, Rohan Alibutud, Robert J Connacher, Madeline St Thomas, Xiaofeng Zhou, Paul Matteson, Jinchuan Xing, James H Millonig, Emanuel DiCicco-Bloom   +11 more
doaj   +1 more source

In vitro uniaxial stretch model for evaluating the effect of strain along axon on damage to neurons

Journal of Biomechanical Science and Engineering, 2014
Diffuse axonal injury (DAI), a major component of traumatic brain injury, is associated with rapid deformation of brain tissue resulting in the stretching of neuronal axons.
Hiromichi NAKADATE, Yohei FUKUMURA, Yuma KANEKO, Akira KAKUTA, Hidenori FURUKAWA, Shigeru AOMURA   +5 more
doaj   +1 more source

A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression. [PDF]

PLoS ONE, 2014
Degeneration of basal forebrain cholinergic neurons contributes significantly to the cognitive deficits associated with Alzheimer's disease (AD) and has been attributed to aberrant signaling through the neurotrophin receptor p75 (p75NTR).
Danielle A Simmons, Juliet K Knowles, Nadia P Belichenko, Gargi Banerjee, Carly Finkle, Stephen M Massa, Frank M Longo   +6 more
doaj   +1 more source

Biomass measurements of single neurites in vitro using optical wavefront microscopy

, 2022
International audienceQuantitative phase microscopies (QPMs) enable label-free, non-invasive observation of living cells in culture, for arbitrarily long periods of time.
Roueff, Antoine, Blivet, Guillaume, Durdevic, Ljiljana, Relaño Ginés, Aroa, Baffou, Guillaume   +4 more
core   +1 more source

Lectin binding to neurites of goldfish retinal explants [PDF]

, 1982
The lectin binding characteristics of goldfish retinal explants were examined by fluoresence microscopy. Neurites grown out from cultured retinal explants were found to bind concanavalin A, wheat germ agglutinin and ricin (agglutinin).
Feldman, Eva L., Heacock, Anne M., Agranoff, Bernard W.   +2 more
core   +1 more source

Sarsasapogenin Improves Pathological Phenotypes in MPTP/MPP+-Induced Parkinson’s Disease Models: Synergistic Actions of Neurite Outgrowth, Neurotransmitter Modulation, and Anti-Inflammation

Journal of Integrative Neuroscience
Background:Parkinson’s disease (PD) is a prevalent neurodegenerative disorder hallmarked by progressive loss of midbrain dopaminergic (DA) neurons, neurite atrophy, neurotransmitter imbalance, and motor dysfunction.
Wendi Deng, Jinfeng Hong, Weixia Li, Yi Zhang, Yongping Zhang, Zhiyou Yang   +5 more
doaj   +1 more source

Polyglutamine-containing microglia leads to disturbed differentiation and neurite retraction of neuron-like cells

Heliyon, 2020
Expanded polyglutamine-containing proteins in neurons intrinsically contributes to neuronal dysfunctions and neuronal cell death in polyglutamine (polyQ) diseases.
Ryuji Owada, Saaya Awata, Kazutomo Suzue, Hiroyasu Kanetaka, Yohei Kakuta, Kazuhiro Nakamura   +5 more
doaj   +1 more source

MCN1 neurites arborize in the anterior CoG.

, 2015
(A) A single optical slice includes a portion of MCN1 (intracellular fill with Alexa 568; green) and DIC optics to view the outline of the tissue. The MCN1 neurites are located in the anterior region of the CoG (bracket), while in this example, the soma ...
Shanna E. Swallie (826255), Alexis M. Monti (826256), Dawn M. Blitz (250696)   +2 more
core   +1 more source

Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography [PDF]

, 2014
Neurites, both dendrites and axons, are neuronal cellular processes that enable the conduction of electrical impulses between neurons. Defining the structure of neurites is critical to understanding how these processes move materials and signals that ...
Shahmoradian, Sarah H, Mobley, William C., Galiano, Mauricio Raul, Wu, Chengbiao, Galiano, Mauricio R, Mobley, William C, Shahmoradian, Sarah H., Rasband, Matthew N., Chiu, Wah, Rasband, Matthew N, Chen, Shurui   +10 more
core   +1 more source