Results 91 to 100 of about 185,865 (259)

Adult-onset Renal Neuroblastoma: Case Report and Literature Review

open access: yesJournal of Cancer Research and Practice
Neuroblastoma is an extremely rare neoplasm in adults, with a poorer prognosis compared to pediatric neuroblastoma. Due to its rarity, there are no specific treatment guidelines for adult neuroblastoma. Here, we report a case of adult renal neuroblastoma
Yao-Ren Yang, Cih-En Huang
doaj   +1 more source

Surgical Management of Giant L2 Adrenal Neuroblastoma in Adult Male

open access: yesCase Reports in Urology, 2020
Neuroblastoma is an embryonal malignancy that arises from neural crest cells. Adult adrenal neuroblastoma is a rare disease, and less than 100 cases were reported in the literature.
Bikash Bikram Thapa   +4 more
doaj   +1 more source

Endocrine-gland vascular endothelial growth factor (EG-VEGF) in neuroblastoma tumor initiating cells

open access: yes, 2010
The 14th Advances in Neuroblastoma Research Conference (ANR 2010), Stockham, Sweden, 21-24 June ...
Tam, PKH   +7 more
core  

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

open access: yesAdvanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai   +10 more
wiley   +1 more source

Novel Inflammatory Mediators in Neuroblastoma Tumorigenesis [PDF]

open access: yes, 2019
The tumor microenvironment is a dynamic, constantly evolving interplay between tumor cells, immune cells, endothelial and other stromal cells, and the extracellular matrix.
Tümmler, Conny
core  

Monoclonal Antibody Therapies for High Risk Neuroblastoma

open access: yes, 2021
Wayne L Furman Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USACorrespondence: Wayne L FurmanDepartment of Oncology, St.
Furman WL
core  

Zinc Fingers as Programmable Metalloprotein Scaffolds for Altering Pathogenic Biomolecular Phase Transitions

open access: yesAdvanced Science, EarlyView.
Modular zinc finger (ZF) metalloproteins function as programmable biomolecular scaffolds that modulate pathogenic amyloid assembly. Through direct protein–protein interactions, ZF arrays alter amyloid phase behavior and redirect β‐sheet fibrillization toward nontoxic aggregates.
Seongmin Park   +16 more
wiley   +1 more source

Epigenetic Silencing of CYYR1 Promotes Lung Adenocarcinoma Progression Through TRIM21‐Dependent Regulation of HMMR Stability

open access: yesAdvanced Science, EarlyView.
CYYR1 as an epigenetically dysregulated tumor‐suppressive factor that influences oncoprotein stability through TRIM21‐dependent HMMR regulation and reveals a potential therapeutic vulnerability in CYYR1‐deficient LUAD. The graphical illustration was created using FigDraw (www.figdraw.com).
Fengsheng Dai   +15 more
wiley   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

Clinical prognostic risk model optimization based on vascular density in neuroblastoma [PDF]

open access: yesPediatr Investig
This study integrates lymphatic vessel density with the International Neuroblastoma Risk Group (INRG) risk classification to develop a more accurate clinical prognostic model for neuroblastoma, demonstrating superior discrimination, calibration, and clinical net benefit compared with the INRG risk classification alone.
Liu Q   +15 more
europepmc   +2 more sources

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