Results 131 to 140 of about 268,028 (214)

The Effect of DNA Methylation on TP73 Expression in Tumorgenesis [PDF]

, 2018
: The Effect of DNA Methylation on TP73 Expression in Tumorgenesis Nujuma Moussa, Zhixing Yao, Zaki A. Sherif Department of Biochemistry & Molecular Biology, Howard University College of Medicine TP73 is a member of the TP53 family of proteins that acts ...
Moussa, Nujuma A
core   +1 more source

Neuroblastoma: nutritional strategies as supportive care in pediatric oncology [PDF]

arXiv
Neuroblastoma, is a highly heterogeneous pediatric tumour and is responsible for 15% of pediatric cancer-related deaths. The clinical outcomes can vary from spontaneous regression to high metastatic disease. This extracranial tumour arises from a neural crest-derived cell and can harbor different phenotypes. Its heterogeneity may result from variations
arxiv  

Guarding against Spurious Discoveries in High Dimensions [PDF]

arXiv, 2015
Many data mining and statistical machine learning algorithms have been developed to select a subset of covariates to associate with a response variable. Spurious discoveries can easily arise in high-dimensional data analysis due to enormous possibilities of such selections. How can we know statistically our discoveries better than those by chance?
arxiv  

Group induced graphical lasso allows for discovery of molecular pathways-pathways interactions [PDF]

arXiv, 2018
Complex systems may contain heterogeneous types of variables that interact in a multi-level and multi-scale manner. In this context, high-level layers may considered as groups of variables interacting in lower-level layers. This is particularly true in biology, where, for example, genes are grouped in pathways and two types of interactions are present:
arxiv  

MMLNB: Multi-Modal Learning for Neuroblastoma Subtyping Classification Assisted with Textual Description Generation [PDF]

arXiv
Neuroblastoma (NB), a leading cause of childhood cancer mortality, exhibits significant histopathological variability, necessitating precise subtyping for accurate prognosis and treatment. Traditional diagnostic methods rely on subjective evaluations that are time-consuming and inconsistent.
arxiv  

Automated segmenta-on of pediatric neuroblastoma on multi-modal MRI: Results of the SPPIN challenge at MICCAI 2023 [PDF]

arXiv
Surgery plays an important role within the treatment for neuroblastoma, a common pediatric cancer. This requires careful planning, often via magnetic resonance imaging (MRI)-based anatomical 3D models. However, creating these models is often time-consuming and user dependent.
arxiv  

Towards Accurate and Interpretable Neuroblastoma Diagnosis via Contrastive Multi-scale Pathological Image Analysis [PDF]

arXiv
Neuroblastoma, adrenal-derived, is among the most common pediatric solid malignancies, characterized by significant clinical heterogeneity. Timely and accurate pathological diagnosis from hematoxylin and eosin-stained whole-slide images is critical for patient prognosis.
arxiv  

Wilms\u27 Tumor and Neuroblastom: Results of Therapy [PDF]

, 1973
Wilms\u27 tumor and neuroblastoma are numerically among the most common noncerebral malignant solid tumors in children.
Maurer, Harold M.
core   +1 more source

Interpretable Embeddings for Segmentation-Free Single-Cell Analysis in Multiplex Imaging [PDF]

arXiv
Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However, current computational pipelines rely on cell segmentation algorithms, which require laborious fine-tuning and can
arxiv  

Interim Analysis in Sequential Multiple Assignment Randomized Trials for Survival Outcomes [PDF]

arXiv
Sequential multiple assignment randomized trials mimic the actual treatment processes experienced by physicians and patients in clinical settings and inform the comparative effectiveness of dynamic treatment regimes. In such trials, patients go through multiple stages of treatment, and the treatment assignment is adapted over time based on individual ...
arxiv