Results 141 to 150 of about 137,730 (260)

A five-gene TAM and MYCN signature predicts prognosis and identifies MTHFD2 as a therapeutic target in neuroblastoma. [PDF]

Discov Oncol
Huang Y, Gao Z, Liang W, Su Z, Mo Y, Wu H.   +5 more
europepmc   +1 more source

Mechanochemically Programmed, Oligomer‐Selective Amyloid Assembly via Axial Rotation

Small, EarlyView.
Tunable axial rotation mechanically redirects amyloid assembly without chemical additives. Low rotational speeds favor fibril maturation, whereas high‐speed rotation suppresses productive fibril amplification and biases the pathway toward oligomer‐enriched assemblies.
Seokbeom Roh, Eunji Song, Minwoo Bae, Da Yeon Cheong, Sechan Han, Taeha Lee, Dain Kang, Jae Eon Lee, Seung Pil Pack, Hyungbeen Lee, Insu Park, Gyudo Lee   +11 more
wiley   +1 more source

VLX1570 suppresses neuroblastoma growth through inhibition of PCNA-associated proliferative signaling and potentiates cisplatin antitumor activity. [PDF]

Front Pharmacol
Yang WH, Khoi CS, Kuo KL, Chow PM, Hsu CH, Kao YJ, Lin WC, Chang SJ, Liao SM, Tai F, Shi CS, Liu SH, Chang PJ, Wang CC, Huang KH.   +14 more
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Adult-Onset Central Nervous System Embryonal Tumor With Neuronal Differentiation: A Diagnostic Challenge. [PDF]

Am J Case Rep
Pham AQ, Pham TV, Pham TM.
europepmc   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

Case Report: Evolution of intratumoral spatial heterogeneity assessed by [⁶⁸Ga]Ga-DOTA-NOC PET/CT during dinutuximab beta therapy in pediatric high-risk neuroblastoma. [PDF]

Front Pediatr
Chen Y, Xu Q, Zhang H, Fang Y, Shao G.
europepmc   +1 more source

Environmental Mycotoxins and Brain Health: Protective Role of Bromelain Against Fumonisin B1 in SH‐SY5Y Cells

Environmental Toxicology, EarlyView.
ABSTRACT Fumonisin B1 (FB1), a mycotoxin commonly found in contaminated food and feed, has been increasingly implicated in neurotoxicity, although its mechanisms remain poorly understood. This study investigates the neurotoxic potential of FB1 in human SH‐SY5Y neuroblastoma cells, both undifferentiated and RA‐differentiated, and evaluates the ...
Gianluca Antonio Franco, Francesca Inferrera, Nicla Tranchida, Davide Di Paola, Roberta Fusco, Salvatore Cuzzocrea, Enrico Gugliandolo   +6 more
wiley   +1 more source

A taurine metabolism-related gene program defines clinical and biological features of neuroblastoma and yields an 8-gene candidate prognostic model. [PDF]

Transl Pediatr
Zhong B, Zhang Y, Wang Z, Dong Q, Li X, Xia Y.   +5 more
europepmc   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan, Brian Sheng Yep Yeo, Manish Warrier, Jun He Chan, Lu Hui Png, Shuhui Xu, Kimberley LiQin Kiong, Edward C. Kuan, Tze Choong Charn, Neville Wei Yang Teo   +9 more
wiley   +1 more source