Results 301 to 310 of about 345,011 (339)

Pathway for the Development of ATR Inhibitors in Pediatric Malignancies: An ACCELERATE Multistakeholder Analysis. [PDF]

JCO Precis Oncol
Gatz SA, Glade-Bender J, Pearson ADJ, Ortiz MV, Bernardi R, Chesler L, Clifford S, Cohen-Gogo S, De La Cuesta E, de Rojas T, Durinck K, Federico S, Fox E, George S, Gounaris I, Henssen AG, Irwin M, Kool M, Lau A, Nysom K, Pappo A, Pennock GK, Pfister SM, Scobie N, Slotkin EK, Smith M, Speleman F, Stewart EA, Weigel BJ, Vassal G.   +29 more
europepmc   +1 more source

Pediatric autologous peripheral blood stem cell collection without heparin using a highly concentrated sodium citrate anticoagulant: A retrospective comparison with standard ACD‐A

Transfusion, EarlyView.
Abstract Background Heparin combined with sodium citrate has been used in leukocytapheresis for pediatric patients. Since 2022, we have performed leukocytapheresis using a highly concentrated sodium citrate solution (HSC, 5.32%) instead of acid citrate dextrose solution A (ACD‐A).
Keiko Fujii, Wataru Kitamura, Kana Washio, Kazuhiro Ikeuchi, Joji Shimono, Hiroyuki Murakami, Fumio Otsuka, Yoshinobu Maeda, Nobuharu Fujii   +8 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

HIF2α negatively regulates MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma. [PDF]

Proc Natl Acad Sci U S A
Yuan J, Maitra S, Antoniou E, Zhu J, Li W, Demirel IS, Toskas K, Martinez IL, Ozcimen L, Lindehell H, Muhr J, Stenman J, Kogner P, Bedoya-Reina OC, Schlisio S, Holmberg J.   +15 more
europepmc   +1 more source

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Busulfan and melphalan (Bu-Mel) versus carboplatin, etoposide, and melphalan (CEM) conditioning regimens for autologous haematopoietic stem cell transplant in children and young adults with high-risk neuroblastoma. [PDF]

Cochrane Database Syst Rev
Gupta AK, Meena JP, Bansal S, Sarangarajan S, Komal M, Sankar MJ.   +5 more
europepmc   +1 more source

Incidence patterns and temporal trends of childhood cancer in Germany, 1980–2019: Forty years of childhood cancer registration in Germany

International Journal of Cancer, Volume 158, Issue 6, Page 1541-1554, 15 March 2026.
What's new? Childhood cancer ranks among the leading causes of disease‐related deaths in children in high‐income countries. Established risk factors, however, account for only a small proportion of incident childhood cancers. In this report, the authors present the first long‐term assessment of temporal trends in childhood cancer incidence rates in ...
Friederike Erdmann, Maike Wellbrock, Claudia Trübenbach, Desiree Grabow, Martin Schrappe, Peter Kaatsch, Claudia Spix, Joachim Schüz, Cécile M. Ronckers   +8 more
wiley   +1 more source

6-Aminonicotinamide enhances the efficacy of 5-aminolevulinic acid-mediated photodynamic therapy for neuroblastoma. [PDF]

BMC Cancer
Okamura SM, Chelakkot VS, Linn Z, Onishi Y, Nakahata K, Toyoda H, Hori H.   +6 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Causal links between congenital malformations, birth weight, and neuroblastoma: insights from Mendelian randomization. [PDF]

BMC Pediatr
Aierken A, Atabieke F, Aizezi Y, Aierken M, Li SX, Zhou L.   +5 more
europepmc   +1 more source