Results 301 to 310 of about 283,064 (357)
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Lancet, The, 2007
Neuroblastomas continue to remain a clinical challenge, despite advances in multimodal therapy. Currently, studies are aimed at novel targets for neuroblastoma directed toward poor prognostic indicators such as the MYCN oncogene and marked angiogenesis.
John M Maris +2 more
exaly +5 more sources
Neuroblastomas continue to remain a clinical challenge, despite advances in multimodal therapy. Currently, studies are aimed at novel targets for neuroblastoma directed toward poor prognostic indicators such as the MYCN oncogene and marked angiogenesis.
John M Maris +2 more
exaly +5 more sources
NEUROBLASTOMA (NEUROBLASTOMA SYMPATHETICUM)
Pediatrics, 1955It has been shown that neuroblastoma can be controlled by irradiation even after extensive spread. It must be agreed that in some instances it is highly unlikely that cancerocidal doses could have reached all the tumor cells. With the knowledge that this tumor may occasionally spontaneously regress or mature into a benign ganglioneuroma, it may be ...
E M, UHLMANN, C, VON ESSEN
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Nature Reviews Disease Primers, 2016
Neuroblastoma is the most common extracranial solid tumour occurring in childhood and has a diverse clinical presentation and course depending on the tumour biology. Unique features of these neuroendocrine tumours are the early age of onset, the high frequency of metastatic disease at diagnosis and the tendency for spontaneous regression of tumours in ...
Katherine K, Matthay +6 more
openaire +4 more sources
Neuroblastoma is the most common extracranial solid tumour occurring in childhood and has a diverse clinical presentation and course depending on the tumour biology. Unique features of these neuroendocrine tumours are the early age of onset, the high frequency of metastatic disease at diagnosis and the tendency for spontaneous regression of tumours in ...
Katherine K, Matthay +6 more
openaire +4 more sources
Urologic Clinics of North America, 1977
Neuroblastoma is the most common solid malignant tumor in children. The prognosis is poor, and despite varying chemotherapy and radiation regimens, its status has not been altered much in the past 20 years. Seventy per cent of the patients have abdominal neuroblastomas, which carry the worst prognosis of all the possible sites for the disease.
J W, Duckett, C E, Koop
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Neuroblastoma is the most common solid malignant tumor in children. The prognosis is poor, and despite varying chemotherapy and radiation regimens, its status has not been altered much in the past 20 years. Seventy per cent of the patients have abdominal neuroblastomas, which carry the worst prognosis of all the possible sites for the disease.
J W, Duckett, C E, Koop
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Pediatric Clinics of North America, 1985
Neuroblastoma originates in the adrenal medulla or anywhere in the body that sympathetic tissue normally is present. It may present with a variety of symptoms due to primary tumor, metastatic disease, or unusual signs and symptoms such as opsoclonus-myoclonus or severe diarrhea.
B, López-Ibor, A D, Schwartz
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Neuroblastoma originates in the adrenal medulla or anywhere in the body that sympathetic tissue normally is present. It may present with a variety of symptoms due to primary tumor, metastatic disease, or unusual signs and symptoms such as opsoclonus-myoclonus or severe diarrhea.
B, López-Ibor, A D, Schwartz
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Urologic Clinics of North America, 2000
Neuroblastoma is a malignant tumor of neural crest origin that may arise anywhere along the sympathetic ganglia or within the adrenal medulla. The median age of diagnosis is 2 years; however occurrence is skewed toward younger children, with nearly 35% of cases occurring under 1 year of age and the remainder under 10 years of age.
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Neuroblastoma is a malignant tumor of neural crest origin that may arise anywhere along the sympathetic ganglia or within the adrenal medulla. The median age of diagnosis is 2 years; however occurrence is skewed toward younger children, with nearly 35% of cases occurring under 1 year of age and the remainder under 10 years of age.
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The Indian Journal of Pediatrics, 1998
The neuroblastic tumours originate from primordial neural crest cells that normally develop into sympathetic nervous system, including the adrenal medulla. Neuroblastoma is the most intriguing pediatric neoplasm displaying diverse clinical and biologic characteristics and natural history.
S, Shah, Y, Ravindranath
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The neuroblastic tumours originate from primordial neural crest cells that normally develop into sympathetic nervous system, including the adrenal medulla. Neuroblastoma is the most intriguing pediatric neoplasm displaying diverse clinical and biologic characteristics and natural history.
S, Shah, Y, Ravindranath
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Pediatric Annals, 1988
The identification of prognostic factors has greatly facilitated the rational choice of therapies in individual patients. Intensive chemotherapy, supplemented with radiation and surgery, has increased the remission rate of patients with widespread disease.
B H, Kushner, N K, Cheung
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The identification of prognostic factors has greatly facilitated the rational choice of therapies in individual patients. Intensive chemotherapy, supplemented with radiation and surgery, has increased the remission rate of patients with widespread disease.
B H, Kushner, N K, Cheung
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World Journal of Urology, 1995
Neuroblastoma, a disease primarily of infants and younger children, is a tumor deriving from sympathetic neuroblasts. The variety of tumor location, growth and biologic characteristics represents the clinical manifestations: the range comprises spontaneous regression up to eminently malignant development with resistance to any therapy.
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Neuroblastoma, a disease primarily of infants and younger children, is a tumor deriving from sympathetic neuroblasts. The variety of tumor location, growth and biologic characteristics represents the clinical manifestations: the range comprises spontaneous regression up to eminently malignant development with resistance to any therapy.
openaire +2 more sources
Critical Reviews in Oncogenesis, 2015
Neuroblastoma is the most common extracranial solid tumor in children. Since its first description some 150 years ago, its enigmatic clinical presentation has challenged clinicians and fascinated basic researchers. This article presents an overview of the key clinical features of neuroblastoma and current therapeutic approaches.
Schulte, Johannes, Eggert, Angelika
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Neuroblastoma is the most common extracranial solid tumor in children. Since its first description some 150 years ago, its enigmatic clinical presentation has challenged clinicians and fascinated basic researchers. This article presents an overview of the key clinical features of neuroblastoma and current therapeutic approaches.
Schulte, Johannes, Eggert, Angelika
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