Altered intrinsic functional coupling between core neurocognitive networks in Parkinson\u27s disease [PDF]
Parkinson3s disease (PD) is largely attributed to disruptions in the nigrostriatal dopamine system. These neurodegenerative changes may also have a more global effect on intrinsic brain organization at the cortical level.
Cronin-Golomb, Alice +4 more
core +1 more source
Environmental and genetic influences on neurocognitive development: the importance of multiple methodologies and time-dependent intervention [PDF]
Genetic mutations and environmental factors dynamically influence gene expression and developmental trajectories at the neural, cognitive, and behavioral levels.
Bryson S. E. +7 more
core +2 more sources
Neonatal Seizures in Tuberous Sclerosis Complex: A Case Series
ABSTRACT Background Epilepsy affects up to 90% of patients with tuberous sclerosis complex (TSC); earlier seizure onset is associated with worse neurocognitive outcomes. The incidence of neonatal seizures in TSC is unknown, although in a recent multicenter trial 23% of infants with TSC were excluded prior to randomization because of pre‐existing ...
Kristina Jülich, Kristen Arredondo
wiley +1 more source
Catatonia and neurocognitive disorder in the context of schizophrenia spectrum disorders
Background. Currently, researchers are aiming to establish the relationship between neurocognitive disorder and other clinical manifestations of endogenous diseases and functional indicators of the patient’s adaptation to social life.
S. I. Ignateva
doaj +1 more source
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo +8 more
wiley +1 more source
Prefronto-cerebellar transcranial direct current stimulation increases amplituded and decreases latency of P3b component in patients with euthymic bipolar disorder [PDF]
INTRODUCTION: Neurocognitive impairments have been observed in patients with bipolar disorder (BD) even during the euthymic phase of the disease, potentially representing trait-associated rather than state-associated characteristics of the disorder.
BERNABEI, LAURA +12 more
core +2 more sources
ABSTRACT Background Large language models (LLMs) are increasingly used to obtain health information, including guidance on child and adolescent mental health. In anorexia nervosa (AN), where early recognition and timely intervention are critical, the accuracy of AI‐generated information available to parents may have important clinical implications ...
Celal Yeşilkaya +4 more
wiley +1 more source
Cognition broadly refers to the ability to perform mental processes such as learning and memory, attention, emotional awareness, and higher-order thinking.
Lillia C. Lucas +4 more
doaj +1 more source
Biochemical and clinical response after umbilical cord blood transplant in a boy with early childhood-onset beta-mannosidosis. [PDF]
BACKGROUND: Deficiency in the enzyme β-mannosidase was described over three decades ago. Although rare in occurrence, the presentation of childhood-onset β-mannosidase deficiency consists of hypotonia in the newborn period followed by global development ...
Eisengart, Julie B. +8 more
core +1 more source
The Psychodynamic Diagnostic Manual – 2nd edition (PDM-2) [PDF]
For decades many clinicians, especially psychodynamic and humanistic therapists, have resisted thinking about their patients in terms of categorical diagnoses.
Blagov +20 more
core +1 more source

