Results 71 to 80 of about 364,044 (282)

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

A bayesian network model for neurocognitive disorders digital screening in Chinese population: development and validation study

BMC Psychiatry
Background Neurocognitive disorders (NCDs), classified under the ICD-10 codes F00-F09, are a category of mental disorders associated with brain disease, injury, or systemic conditions leading to cerebral dysfunction.
Yifan Yu, Shuaijie Zhang, Hongkai Li, Fuzhong Xue   +3 more
doaj   +1 more source

High prevalence of neurocognitive disorders observed among adult people living with HIV/AIDS in Southern Ethiopia: A cross-sectional study.

PLoS ONE, 2019
BACKGROUND:Comprehensive care given to people living with HIV/AIDS is improving over time; however, their concurrent cognitive illness is still ignored, under screened and treated particularly in developing countries. And this problem is also striking in
Megbaru Debalkie Animut, Muluken Bekele Sorrie, Yinager Workineh Birhanu, Manaye Yihune Teshale   +3 more
doaj   +1 more source

Disruption to control network function correlates with altered dynamic connectivity in the wider autism spectrum. [PDF]

, 2017
Autism is a common developmental condition with a wide, variable range of co-occurring neuropsychiatric symptoms. Contrasting with most extant studies, we explored whole-brain functional organization at multiple levels simultaneously in a large subject ...
Calhoun, VD, de Lacy, N, Doherty, D, King, BH, Rachakonda, S   +4 more
core   +1 more source

Hyperostosis frontalis interna: Observed patterns, prevalence, and dementia associations in older adults

The Anatomical Record, EarlyView.
Abstract Hyperostosis frontalis interna (HFI) is a frequently underrecognized condition characterized by overgrowth of the frontal endocranium, most commonly observed in post‐menopausal women. Although its etiology remains unclear, hormonal influences and a possible relationship with neurocognitive changes have been proposed.
Danielle Felsberg, Kira Morgan, Rickey‐Levon Burch, Madelyn Furr, Zachary Tyson, Steven Lesh   +5 more
wiley   +1 more source

Association of cognitive function and phase angle in older adults with cognitive impairment

Archives of Gerontology and Geriatrics Plus
Phase angle (PhA) has garnered increasing attention; however, its relationship with cognitive function has not been fully elucidated. This cross-sectional study explores the relationship between PhA using bioelectrical impedance analysis, and cognitive ...
Derong Zeng, Hiroyuki Nishimoto, Teruaki Kawasaki, Ichiro Akiguchi, Kayoko Fukui, Ayae Kinoshita   +5 more
doaj   +1 more source

A Roadmap for Integrating Neuroscience into Addiction Treatment:A Consensus of the Neuroscience Interest Group of the International Society of Addiction Medicine [PDF]

, 2019
Although there is general consensus that altered brain structure and function underpins addictive disorders, clinicians working in addiction treatment rarely incorporate neuroscience-informed approaches into their practice.
Arunogiri, Shalini, Baldacchino, Alex, Bates, Marsha E., Bowden-Jones, Henrietta, Bruno, Raimondo, Campanella, Salvatore, Daughters, Stacey, Ekhtiari, Hamed, Hester, Rob, Kouimtsidis, Christos, Lorenzetti, Valentina, Lubman, Dan I., Manning, Victoria, Meyerhoff, Dieter J., Moeller, Scott J., Paulus, Martin P., Pennington, David, Piercy, Hugh, Ralph, Annaketurah, Rezapour, Tara, Steele, Douglas, Tavakoli, Hosna, Tolomeo, Serenella, Verdejo-Garcia, Antonio, Zare-Bidoky, Mehran, Zilverstand, Anna   +25 more
core   +7 more sources

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Magnitude of Neurocognitive Impairment and Severity of Depression in Geriatric Population

BioMedica, 2020
Background and Objective:  With the increasing life expectancy of the populations and rising prevalence of depressive and neurocognitive disorders, there is a need to address the association between the two in terms of magnitude of the ...
Sadia Yasir, Saad Bin Yasir, Nariman Haider, Sundas Fatima, Mahpara Mazhar, Saima Chaudhry, Asad Tamizuddin Nizami   +6 more
doaj   +1 more source