Results 141 to 150 of about 3,341,463 (362)

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study

Epilepsia, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is a rare X‐linked developmental and epileptic encephalopathy caused by loss‐of‐function variants in the CDKL5 gene. Preclinical experiments using enzyme replacement or gene therapies show promise and could be transformative therapies.
Xavier Liogier d'Ardhuy, CANDID Partners, Tricia Cimms, Kristina Lindsten, Marco Rizzo, Alison Skrinar, Peter St. Wecker, Ana Mingorance, Orrin Devinsky   +8 more
wiley   +1 more source

"Older Adults with ASD: The Consequences of Aging." Insights from a series of special interest group meetings held at the International Society for Autism Research 2016-2017 [PDF]

, 2019
A special interest group (SIG) entitled "Older Adults with ASD: The Consequences of Aging" was held at the International Society for Autism Research (INSAR) annual meetings in 2016 and 2017. The SIG and subsequent meetings brought together, for the first
A. Roestorf, Anderson, Autism Canada, Autistica, Autistica, Ayres, B.F.C. Van Heijst, Bagby, Baron-Cohen, Bauman, Bishop, Boucher, Bowler, Braden, Braden, Brugha, Bölte, Bölte, Cappelletti, Charlton, Constantino, Constantino, Coppus, Craik, Craik, Craik, Craik, Croen, Crook, Cummins, Cummins, D.M. Bowler, Damiano, Davis, de Vent, Dempster, D’Astous, Evans, Ferreira, Fortuna, Friedman, H. McConachie, H.M. Geurts, Happé, Happé, Hedden, Hill, Hirvikoski, Hoekstra, Hoekstra, Hofvander, Howlin, Howlin, Howlin, Howlin, Howlin, Information Commissioner’s Office, J.R. Parr, Joss, Just, Kats, Kenny, Knapp, L. Klinger, Lai, Lever, Lever, Lever, Lewis, M.K. Deserno, Mandy, Mason, McCabe, McClintock, McConachie, McDaniel, Michael, Minshew, Moss, Mottron, Mouridsen, Mukaetova-Ladinska, Mäntylä, National Autistic Society, Nicolaidis, Oberman, Oberman, P. Howlin, P. Powell, Parr, Pellicano, Pellicano, Powell, Prince, Rabbitt, Raz, Roestorf, Roestorf, Roestorf, Rutter, Salthouse, Salthouse, Salthouse, Salthouse, Schalock, Seltzer, Skevington, Smith, South, Starkstein, Starkstein, Stuart-Hamilton, Tennant, Totsika, van Heijst, Wakabayashi, Warner, WHOQOL Group, Wigham, Woods, Wright, Zerbo   +121 more
core   +4 more sources

Depressive symptoms as independent correlates of epilepsy‐related cognitive burden

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to assess the relationship between the severity of depression and anxiety symptoms and epilepsy‐related variables and cognitive burden in people with epilepsy (PwE), as assessed using EpiTrack. Methods We prospectively enrolled a cohort of PwE who underwent EpiTrack and evaluation by Generalized Anxiety ...
Biagio Maria Sancetta, Giuli Lippa, Marianna Nesta, Lorenzo Ricci, Simona Paola Carbone, Lorenzo Veronese, Giulia Conti, Marco Sferruzzi, Vincenzo Di Lazzaro, Mario Tombini, Giovanni Assenza   +10 more
wiley   +1 more source

Dementia assessment and management in primary care settings: a survey of current provider practices in the United States. [PDF]

, 2019
BACKGROUND:Primary care providers (PCPs) are typically the first to screen and evaluate patients for neurocognitive disorders (NCDs), including mild cognitive impairment and dementia. However, data on PCP attitudes and evaluation and management practices
Bernstein, Alissa, Geschwind, Michael, Higgins, Joseph J, Kramer, Joel H, Miller, Bruce L, Pesano, Rick, Possin, Katherine L, Rankin, Katherine P, Ritchie, Christine S, Rogers, Kirsten M, Steele, Natasha ZR, Wohlgemuth, Jay   +11 more
core   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

AI-assisted neurocognitive assessment protocol for older adults with psychiatric disorders

Frontiers in Psychiatry
IntroductionEvaluating neurocognitive functions and diagnosing psychiatric disorders in older adults is challenging due to the complexity of symptoms and individual differences. An innovative approach that combines the accuracy of artificial intelligence
Diego D. Díaz-Guerra, Marena de la C. Hernández-Lugo, Yunier Broche-Pérez, Carlos Ramos-Galarza, Ernesto Iglesias-Serrano, Zoylen Fernández-Fleites   +5 more
doaj   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Executive functions as a potential neurocognitive endophenotype in anxiety disorders: A systematic review considering DSM-IV and DSM-5 diagnostic criteria classification

Dementia & Neuropsychologia
Evidence in the literature indicates that neurocognitive impairments may represent endophenotypes in psychiatric disorders. Objective: This study aimed to conduct a systematic review on executive functions as a potential neurocognitive endophenotype in ...
Juliana de Lima Muller, Kamilla Irigaray Torquato, Gisele Gus Manfro, Clarissa Marceli Trentini   +3 more
doaj   +1 more source

AI‐based localization of the epileptogenic zone using intracranial EEG

Epilepsia Open, EarlyView.
Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida, Yipeng Zhang, Sotaro Kanai, Richard Staba, Vwani Roychowdhury, Hiroki Nariai   +5 more
wiley   +1 more source

Selective Serotonin Reuptake Inhibitors for Treating Neurocognitive and Neuropsychiatric Disorders Following Traumatic Brain Injury: An Evaluation of Current Evidence [PDF]

, 2017
John K. Yue, John F. Burke, Pavan S. Upadhyayula, Ethan A. Winkler, Hansen Deng, Caitlin Robinson, Romain Pirracchio, Catherine G. Suen, Sourabh Sharma, Adam R. Ferguson, Laura B. Ngwenya, Murray B. Stein, Geoffrey T. Manley, Phiroz E. Tarapore   +13 more
openalex   +1 more source