The Role of Microglia in Perioperative Neuroinflammation and Neurocognitive Disorders
The aseptic trauma of peripheral surgery activates a systemic inflammatory response that results in neuro-inflammation; the microglia, the resident immunocompetent cells in the brain, are a key element of the neuroinflammatory response.
S. Saxena, V. Kruys, J. Vamecq, M. Maze
semanticscholar +1 more source
Major Neurocognitive Disorders describe the symptoms of a large group of diseases causing a progressive decline in individual’s functioning. It is an umbrella term describing a decline in memory, intellectual ability, reasoning, and social skills, as ...
Susana Sousa +7 more
doaj +1 more source
Mycobiota, neuro-cognitif disorders and behavioural impairments: is there a relationship?
Introduction The human body carries large and diverse communities of symbiotic microbes that are important for human health and development. While the impact of the bacterial microbiota, which are mostly found in the human gut, on host physiology is ...
B. Abdelmoula +4 more
doaj +1 more source
Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe
Harmonized neuropsychological assessment for neurocognitive disorders, an international priority for valid and reliable diagnostic procedures, has been achieved only in specific countries or research contexts.
M. Boccardi +57 more
semanticscholar +1 more source
Neurocognitive abilities have frequently been claimed to be involved in the aetiology of psychopathology. Neurocognitive deficits have been reported across many disorders, and theoretical perspectives associate these deficits to the onset and maintenance
Darren Haywood +3 more
doaj +1 more source
Ferroptosis is involved in regulating perioperative neurocognitive disorders: emerging perspectives
Since the twenty-first century, the development of technological advances in anesthesia and surgery has brought benefits to human health. However, the adverse neurological effects of perioperative-related factors (e.g., surgical trauma, anesthesia, etc.)
Yanhong Song, Zi-yi Wu, H. Xue, P. Zhao
semanticscholar +1 more source
Biotypes of HIV-associated neurocognitive disorders based on viral and immune pathogenesis
Purpose of review HIV-associated neurocognitive disorders (HAND) continues to be prevalent in people living with HIV despite antiretroviral therapy. However, understanding disease mechanisms and identifying therapeutic avenues has been challenging.
T. Johnson, A. Nath
semanticscholar +1 more source
Neuroinflammation is a putative target for the prevention and treatment of perioperative neurocognitive disorders. [PDF]
IntroductionThe demographics of aging of the surgical population has increased the risk for perioperative neurocognitive disorders in which trauma-induced neuroinflammation plays a pivotal role.Sources of dataAfter determining the scope of the review ...
Lai, IK, Li, R, Maze, M, Saxena, S
core +2 more sources
Age-Related Perioperative Neurocognitive Disorders: Experimental Models and Druggable Targets.
With the worldwide increase in life span, surgical patients are becoming older and have a greater propensity for postoperative cognitive impairment, either new onset or through deterioration of an existing condition; in both conditions, knowledge of the ...
O. L. B. Chang, K. Possin, M. Maze
semanticscholar +1 more source
The screening for depression and neurocognitive disorders in subjects newly diagnosed with HIV [PDF]
Background Inflammatory mediators may be relevant to explain the frequent comorbidity between depression, neurocognitive disorders and HIV. HIV induces activation of inflammatory mediators, mainly cytokines, that have been involved in the onset of ...
ALBONI, Silvia +6 more
core +1 more source

