Results 71 to 80 of about 4,019,243 (180)

Human cerebral arterial morphogenesis explored by 3D microscopic imaging of cleared embryos: Bridging the gap between embryonic and adult anatomy

Journal of Anatomy, EarlyView.
We provide a description of human embryonic cerebral arterial development based on whole‐mount immunostaining, tissue clearing, three‐dimensional (3D) light‐sheet microscopy imaging, and anatomically informed virtual segmentation of human embryos. Findings are compared with adult radiological anatomy. We provide a detailed account of the development of
Eimad Shotar, Raphaël Blain, Aymeric Nadjem, Nermine Saidi, Megumi Inoue, Daniel Smith‐Paredes, Miccaella Vergara, Armelle Lesaunier, Quentin Rappeneau, Joséphine Blevinal, Gérard Couly, Julien Burel, Julien Allard, Kevin Premat, Stéphanie Lenck, Pierre‐Marie Chiaroni, Erwah Kalsoum, Maryne Toupin, Séverine Mazaud‐Guittot, Diane Rebourcet, Paolo Giacobini, Olivier Naggara, Hugo Gortais, Grégoire Boulouis, Alexis Guédon, Philippe Gailloud, Frédéric Glicenstein, Anaïs Favre, Frédéric Clarençon, Yorick Gitton, Alain Chédotal   +30 more
wiley   +1 more source

Analysis on the training effect of criteria and practical guidance for determination of brain death: clinical diagnosis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective Clinical diagnosis is the most predominant in the criteria for determination of brain death. This paper aims to analyze the training results of clinical diagnosis for brain death determination and to improve the training program.
Ying-ying SU, Yun-zhou ZHANG, Dai-quan GAO, Yan ZHANG, Hong YE, Wei-bi CHEN, Lin-lin FAN   +6 more
doaj  

Temperature variability in the day–night cycle is associated with further intracranial pressure during therapeutic hypothermia

Journal of Translational Medicine, 2017
Background To assess whether circadian patterns of temperature correlate with further values of intracranial pressure (ICP) in severe brain injury treated with hypothermia. Methods We retrospectively analyzed temperature values in subarachnoid hemorrhage
Adriano Barreto Nogueira, Eva Annen, Oliver Boss, Faraneh Farokhzad, Christopher Sikorski, Emanuela Keller   +5 more
doaj   +1 more source

Early plasma administration in traumatic brain injuries: A systematic review

Transfusion, EarlyView.
Abstract Background Early plasma may improve trauma resuscitation by addressing shock and coagulopathy, but its role in traumatic brain injury (TBI) remains uncertain. This systematic review evaluated early plasma in TBI. Methods This review followed Cochrane methodology and was registered in PROSPERO (CRD420261357882).
Umair Tahir, Ian R. Drennan, Peter Kobal, Otis Weeks, Soha Khorsand, Carolyn Ziegler, Melissa McGowan, Brodie Nolan   +7 more
wiley   +1 more source

Analysis on the factors associated with treatment failure of using anesthetics in refractory status epilepticus

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To analyze the related factors associated with immediate treatment failure of using anesthetics in refractory status epilepticus (RSE).  Methods Thirty patients derived from Neurocritical Care Unit of Xuanwu Hospital from January 2004 to ...
Ying-ying SU, Guo-ping REN, Wei-bi CHEN, Yan ZHANG, Hong YE, Dai-quan GAO   +5 more
doaj  

Repetitive Transcranial Magnetic Stimulation Combined With Median Nerve Electrical Stimulation for Severe Traumatic Brain Injury

Brain and Behavior, Volume 16, Issue 10, October 2026.
Combining top‐down rTMS over the left DLPFC with bottom‐up right median nerve stimulation markedly outperformed either modality alone, awakening 93% of patients with severe TBI by week 4 and improving EEG, hemodynamics, and GCS—supporting dual‐pathway neuromodulation as a safe, high‐efficacy strategy for coma recovery.
Nana Wang, Manrong Li, Guozhen Zhang
wiley   +1 more source

Timing of evoked potentials forecasting the prognosis of severe stroke patients

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To investigate the best assessment time of short-latency somatosensory-evoked potential (SLSEP) and brain stem auditory-evoked potential (BAEP) in predicting the prognosis of patients with acute severe stroke.
Shu-ying XIAO, Ying-ying SU, Yan ZHANG, Hong ZHAO, Ying PANG, Yi-fei LIU   +5 more
doaj  

Intraventricular antibiotics for severe central nervous system infections: a case series

Scientific Reports
Severe central nervous system infections (CNSI), including community-acquired CNSI (CA-CNSI) and healthcare-associated ventriculitis and meningitis (HAVM), present high morbidity and mortality. Intraventricular antibiotic treatment (IVT) is advisable for
Laura Arheilger, Massimo Barbagallo, Gaia Sofia Rancic, Federica Stretti, Sabeth Dietler-Ebner, Nicolas J. Mueller, Emanuela Keller, Claudio Togni, Giovanna Brandi   +8 more
doaj   +1 more source

Utility of Bispectral Index Monitor as a Tool to Detect and Manage Intraoperative Seizure: A Case Series

Journal of Neuroanaesthesiology and Critical Care
Conventional electroencephalogram (EEG) has been the most common method to detect and manage seizure episodes. Limitations to its use in the intraoperative period during neurosurgical cases have made detecting intraoperative seizure almost impractical ...
Sandeep Dey, Megha Tyagi, Amit Goyal, Pallav Kumar   +3 more
doaj   +1 more source

CYP2C19 Genotyping to Guide Clopidogrel Prescribing for Neurovascular Indications: A Survey of Institutional Approaches

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 937-942, October 2026.
Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is commonly used for secondary prevention following acute ischemic stroke (AIS) and neurointerventional procedures. However, the efficacy of clopidogrel is reduced in carriers of CYP2C19 no‐function alleles.
Rachael M. Stone, Glenda Hoffecker, April Schultz, Brittney H. Davis, Salma A. Bargal, Amber L. Beitelshees, Nihal El Rouby, Madeline Norris, Kevin J. Rodriguez, Nita Limdi, Larisa H. Cavallari, Craig R. Lee   +11 more
wiley   +1 more source