Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina+12 more
wiley +1 more source
Editorial: Metabolic dysregulation in neurodegenerative diseases. [PDF]
Jimenez-Gonzalez M.
europepmc +1 more source
Neurodegeneration and regeneration [PDF]
openaire +3 more sources
Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim+4 more
wiley +1 more source
Interplay Between Vascular Dysfunction and Neurodegenerative Pathology: New Insights into Molecular Mechanisms and Management. [PDF]
Mekala A, Qiu H.
europepmc +1 more source
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi+6 more
wiley +1 more source
Exploring α-Syn's Functions Through Ablation Models: Physiological and Pathological Implications. [PDF]
Praveen A, Dougnon G, Matsui H.
europepmc +1 more source
Mitochondria‐Nuclear Crosstalk: Orchestrating mtDNA Maintenance
ABSTRACT The mitochondria (mt) and nucleus engage in a dynamic bidirectional communication to maintain cellular homeostasis, regulating energy production, stress response, and cell fate. Anterograde signaling directs mt function, while retrograde signaling conveys metabolic and stress‐related changes from mt to the nucleus. Central to this crosstalk is
Ghazal Darfarin, Janice Pluth
wiley +1 more source
Neurodegeneration and the immune system: lessons from autoimmune encephalitis. [PDF]
Campetella L+6 more
europepmc +1 more source
Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan+7 more
wiley +1 more source