Results 221 to 230 of about 366,723 (337)

Poster Session C22: Neurodegeneration [PDF]

, 2000

openalex   +1 more source

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

Non-mutated human tau stimulates Alzheimer's disease-relevant neurodegeneration in a microglia-dependent manner. [PDF]

Sci Rep
Roy ER, Wang Q, Huang K, Li S, Fan Y, Escobar E, Atkins CL, Huang S, Herrera JJ, Li W, Pridans C, Zhou X, Ju C, Cao W.   +13 more
europepmc   +1 more source

Direct Sequencing of 5‐Methylcytosine and 5‐Hydroxymethylcytosine at Single‐Base Resolution Unravels Their Distinct Roles in Alzheimer's Disease

Advanced Science, EarlyView.
This study introduces two orthogonal sequencing methods, CMD1‐Deaminase sequencing (CD‐seq) and CMD1‐TET bisulfite sequencing (CT‐seq), that enable direct, independent detection of 5mC. Using these approaches together with ACE‐seq or TAB‐seq for 5hmC identification, the study reveals a significant reduction in 5hmC, but not 5mC, in the hippocampus of ...
Zi‐Xin Wang, Faying Chen, Bao‐Dan He, Fan‐Chen Wang, Jiaxue Cha, Yu Song, Wei‐Ying Meng, Wan‐Yue Zou, Yu‐Tao Fu, Shu‐Xia Sun, Zhi‐Yan Sun, Hao‐Ming Jiang, Ke‐Yao Zhao, Yujun Hou, Jiejun Shi, Jian‐Huang Xue   +15 more
wiley   +1 more source

Diabetes-Driven Retinal Neurodegeneration: Its Role in the Pathogenesis of Diabetic Retinopathy. [PDF]

Biomedicines
Viganò I, Galbiati S, Aragona E, Gabellini D, Lattanzio R, Pedon V, Basile G, Arrigo A, Bandello F, Zerbini G.   +9 more
europepmc   +1 more source

Poster Session C03: Neurodegeneration [PDF]

, 2000

openalex   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Neuroinflammation in Huntington's disease: Causes, consequences, and treatment strategies. [PDF]

J Huntingtons Dis
Blusch A, Björkqvist M.
europepmc   +1 more source

Bioinspired Engineering beyond Homeostasis

Advanced Intelligent Systems, EarlyView.
This perspective article introduces systems biology as the unifying theoretical framework behind bioinspired engineering. As an example, it explores how disruptions in multiscale biological systems, associated with pathological states, can be viewed as localized failure modes of biological cooperation showing emergent advantages that can inspire ...
Rosalia Moreddu
wiley   +1 more source

Presynaptic loss and axonal degeneration synergistically correlate with longitudinal neurodegeneration and cognitive decline. [PDF]

Alzheimers Dement
Shi D, Ye C, Li A, Sun P, Lan G, Zhang L, Zhou X, Zhou L, Liu Z, Guo T, Alzheimer's Disease Neuroimaging Initiative.   +10 more
europepmc   +1 more source