Results 301 to 310 of about 395,485 (325)

Neurodegeneration

2022
Wave V measures of neurodegeneration were based on venous blood collected via phlebotomy. The blood was collected by field examiners (FEs) certified in phlebotomy, chilled at 4°C during the remainder of the home exam, centrifuged immediately afterward, aliquoted into transport tubes, sent overnight to a laboratory, archived at -80°C, subsequently ...
Harris, Kathleen Mullan, Qu, Lixin, Angel, Robert, Carrier, Kathryn, O'Hara, Rick, Whitsel, Eric A.   +5 more
openaire   +2 more sources

Autophagy and neurodegeneration

Current Neurology and Neuroscience Reports, 2007
All cellular components are subjected to continuous surveillance by intracellular quality control systems. The major players involved in this quality control are molecular chaperones, which detect the abnormal components, and proteases, which eliminate them from the cell.
Annamaria, Ventruti, Ana Maria, Cuervo
openaire   +2 more sources

Neurodegeneration and peroxidases

Neurobiology of Aging, 2009
Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases that affect different parts of the central nervous system. However, a review of the literature indicates that certain biochemical reactions involved in neurodegeneration in these three diseases are quite similar and could be partly ...
Johannes, Everse, Penelope W, Coates
openaire   +2 more sources

Neurotrophins and neurodegeneration

Neuropathology and Applied Neurobiology, 2003
There is growing evidence that reduced neurotrophic support is a significant factor in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS). In this review we discuss the structure and functions of neurotrophins such as nerve growth factor, and the role of ...
Dawbarn, D, Allen, SJ
openaire   +3 more sources

Neurodegeneration

2011
MILARDI D, RIZZARELLI, Enrico, WILLIAMS R. J. P, FRAUSTO DA SILVA J. J. R, SAARANEN M. J, RUDDOCK L. W, CENCI S, SITIA R, KAGAN B. L, GRASSO, GIUSEPPE, LA MENDOLA D, AMADORO G, CALISSANO P, REMBACH A, DUCE J. A, O'SULLIVAN L. A, TANZI R. E, BUSH A. I, ZUCCA F. A, cupaioli f. a, zecca l, bolognin S, ZATTA P, LELIE H. L, WHITELEGGE J. P, BORCHELT D. R, VALENTINE J. S, MILLHAUSER G. L.   +27 more
  +6 more sources

Osteoporosis in neurodegeneration

Journal of Trace Elements in Medicine and Biology, 2014
Osteoporosis affects bone microarchitecture and reduces bone mass. There are more than 200 million people with osteoporosis worldwide, and the prevalence is slowly increasing. The highest prevalences are found in Scandinavia and USA, also slowly increasing.
openaire   +2 more sources

Untangling neurodegeneration

Nature Reviews Neuroscience, 2022
openaire   +2 more sources

Neurodegeneration and plasticity

International Journal of Developmental Neuroscience, 2004
AbstractNeurofibrillary degeneration, associated with the formation of paired helical filaments (PHF), is one of the critical neuropathological hallmarks of Alzheimer's disease (AD). Although the microtubule‐associated protein tau in a hyperphosphorylated form has been established as primary PHF constituent, the process of tau phosphorylation and its ...
openaire   +2 more sources

Neurodegeneration in schizophrenia

Expert Review of Neurotherapeutics, 2010
The neurodegenerative aspect of schizophrenia presupposes gene-environmental interactions involving chromosomal abnormalities and obstetric/perinatal complications that culminate in predispositions that impart a particular vulnerability for drastic and unpredictable precipitating factors, such as stress or chemical agents.
openaire   +2 more sources