Results 11 to 20 of about 18,329 (223)
An international registry for neurodegeneration with brain iron accumulation [PDF]
Orphanet Journal of Rare Diseases, 2012 We report the development of an international registry for Neurodegeneration with Brain Iron Accumulation (NBIA), in the context of TIRCON (Treat Iron-Related Childhood-Onset Neurodegeneration), an EU-FP7 – funded project.
Kalman Bernadette +6 more
doaj +8 more sources
Neurodegeneration with brain iron accumulation [PDF]
Handbook of Clinical Neurology / Edited By P J Vinken and G W Bruyn, 2018 Neurodegeneration with brain iron accumulation (NBIA) comprises a clinically and genetically heterogeneous group of disorders affecting children and adults. These rare disorders are often first suspected when increased basal ganglia iron is observed on brain magnetic resonance imaging.
Susan J Hayflick +2 more
exaly +7 more sources
Neurodegeneration with Brain Iron Accumulation [PDF]
Parkinsonism & Related Disorders, 2015 Syndromes with Neurodegeneration with Brain Iron Accumulation (NBIA) are a group of neurodegenerative disorders characterized by excess iron mainly in the globus pallidus and sometimes adjacent areas. They clinically present as hypo- and/or hyperkinetic movement disorders and a variable degree of pyramidal, cerebellar, peripheral nerve, autonomic ...
Bertelsen, Maria +1 more
core +5 more sources
Neurodegeneration with brain iron accumulation: an overview. [PDF]
Iran J Child Neurol, 2014 Neurodegeneration with brain iron accumulation (NBIA) is a group of neurodegenerative disorder with deposition of iron in the brain (mainly Basal Ganglia) leading to a progressive Parkinsonism, spasticity, dystonia, retinal degeneration, optic atrophy often accompanied by psychiatric manifestations and cognitive decline. 8 of the 10 genetically defined
Tonekaboni SH, Mollamohammadi M.
europepmc +5 more sources
Neurodegeneration with brain iron accumulation
Анналы клинической и экспериментальной неврологии, 2017 Neurodegeneration with brain iron accumulation (NBIA) is aclinically and genetically heterogeneous group of hereditary (predominantlyautosomal recessive) progressive disorders of the CNSwith a common feature of iron accumulation in basal ganglia ...
G. E. Rudenskaya, E. Yu. Zakharova
doaj +5 more sources
MRI of neurodegeneration with brain iron accumulation
Current Opinion in Neurology, 2020 Purpose of review The diagnosis of neurodegeneration with brain iron accumulation (NBIA) typically associates various extrapyramidal and pyramidal features, cognitive and psychiatric symptoms with bilateral hypointensities in the globus pallidus on iron-sensitive magnetic resonance images, reflecting the alteration of iron ...
Lehéricy, Stéphane +3 more
openaire +5 more sources
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration [PDF]
Neural Regeneration Research, 2023 Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García +10 more
doaj +2 more sources
Update on neurodegeneration with brain iron accumulation
Neurologia i Neurochirurgia Polska, 2014 Neurodegeneration with brain iron accumulation (NBIA) defines a heterogeneous group of progressive neurodegenerative disorders characterized by excessive iron accumulation in the brain, particularly affecting the basal ganglia. In the recent years considerable development in the field of neurodegenerative disorders has been observed.
Karolina, Popławska-Domaszewicz +2 more
openaire +4 more sources
A diagnostic approach for neurodegeneration with brain iron accumulation: clinical features, genetics and brain imaging [PDF]
Arquivos de Neuro-Psiquiatria, 2016 Neurodegeneration with brain iron accumulation (NBIA) represents a heterogeneous and complex group of inherited neurodegenerative diseases, characterized by excessive iron accumulation, particularly in the basal ganglia.
Rubens Paulo Araújo Salomão +9 more
doaj +2 more sources
A pilot trial of deferiprone for neurodegeneration with brain iron accumulation [PDF]
Haematologica, 2011 Deferiprone was shown to reverse iron deposition in Friedreich’s ataxia. This multi-center, unblinded, single-arm pilot study evaluated safety and efficacy of deferiprone for reducing cerebral iron accumulation in neurodegeneration with brain iron ...
Giovanni Abbruzzese +11 more
doaj +2 more sources